ET-23 THERAPEUTIC EFFICACY OF RETROVIRAL REPLICATING VECTORS IN HUMAN BREAST CANCER CNS METASTASIS MODEL

Por Inagaki, Akihito, Hiraoka, Kei, Kamijima, Shuichi, Robbins, Joan, Jolly, Douglas, Gruber, Harry, Kasahara, Noriyuki
Publicado em 2014

ET-13 RETROVIRAL REPLICATING VECTOR (RRV)-MEDIATED PRODRUG ACTIVATOR GENE THERAPY WITH CODON-OPTIMIZED NITROREDUCTASE IN EXPERIMENTAL GLIOMA

Por Collins, Sara, Logg, Christopher, Inagaki, Akihito, Kamijima, Shuichi, Lehouritis, Panos, Searle, Peter, Tangney, Mark, Kasahara, Noriyuki
Publicado em 2014

Differential Targeting of Stem Cells and Differentiated Glioblastomas by NK Cells

Por Tseng, Han-Ching, Inagaki, Akihito, Bui, Vickie T., Cacalano, Nicholas, Kasahara, Noriyuki, Man, Yan-gao, Jewett, Anahid
Publicado no J Cancer (2015)

Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural...

Por Kozlowska, Anna K., Tseng, Han-Ching, Kaur, Kawaljit, Topchyan, Paytsar, Inagaki, Akihito, Bui, Vickie T., Kasahara, Noriyuki, Cacalano, Nicholas, Jewett, Anahid
Publicado no Cancer Immunol Immunother (2016)

PDTM-19. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN MEDULLOBLASTOMA

Por Richardson, Angela M, Collins, Sara A, Inagaki, Akihito, Armstrong, Valerie L, Roussel, Martine, Jolly, Douglas, Robbins, David J, Ayad, Nagi, Kasahara, Noriyuki
Publicado no Neuro Oncol (2017)

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model

Por Mitchell, Leah A., Lopez Espinoza, Fernando, Mendoza, Daniel, Kato, Yuki, Inagaki, Akihito, Hiraoka, Kei, Kasahara, Noriyuki, Gruber, Harry E., Jolly, Douglas J., Robbins, Joan M.
Publicado no Neuro Oncol (2017)

TMOD-15. TOCA 511 & TOCA FC: PRE-CLINICAL PROOF OF CONCEPT IN CNS METASTATIC BREAST CANCER

Por Inagaki, Akihito, Richardson, Angela M, Collins, Sara A, Hiraoka, Kei, Kamijima, Shuichi, Shorr, Jolene, Gruber, Harry, Jolly, Douglas, Merchan, Jaime, Slingerland, Joyce M, Kasahara, Noriyuki
Publicado no Neuro Oncol (2017)

STEM-24. THERAPEUTIC APPROACH OF STEM CELL CARRYING RETROVIRAL REPLICATING VECTORS IN HUMAN GLIOMA MODEL

Por Inagaki, Akihito, Takahashi, Masamichi, Kamijima, Shuichi, Hiraoka, Kei, Tam, Quincy, Faure-Kumar, Emmanuelle, Treger, Janet, Bogan, Brooke, Hacke, Katrin, Collins, Sara, Jolly, Douglas, Kasahara, Noriyuki
Publicado no Neuro Oncol (2019)

Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector

Por Takahashi, Masamichi, Valdes, Gilmer, Hiraoka, Kei, Inagaki, Akihito, Kamijima, Shuichi, Micewicz, Ewa, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., McBride, William H., Iwamoto, Keisuke S., Kasahara, Noriyuki
Publicado no Cancer Gene Ther (2014)

Combined Alloreactive CTL Cellular Therapy with Prodrug Activator Gene Therapy in a Model of Breast Cancer Metastatic to the Brain

Por Hickey, Michelle J., Malone, Colin C., Erickson, Kate L., Lin, Amy, Soto, Horacio, Ha, Edward T., Kamijima, Shuichi, Inagaki, Akihito, Takahashi, Masamichi, Kato, Yuki, Kasahara, Noriyuki, Mueller, Barbara M., Kruse, Carol A.
Publicado em 2013

ET-60 ENHANCED THERAPEUTIC EFFICACY OF PRODRUG ACTIVATOR GENE THERAPY WITH A NON-LYTIC RETROVIRAL REPLICATING VECTOR (TOCA 511) COMBINED WITH RADIATION THERAPY IN EXPERIMENTAL GLIO...

Por Takahashi, Masamichi, Valdes, Gilmer, Inagaki, Akihito, Kamijima, Shuichi, Hiraoka, Kei, Micewicz, Ewa, McBride, William H., Iwamoto, Keisuke S., Hermann, Kip, Collins, Sara, Tam, Quincy, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., Kasahara, Noriyuki
Publicado em 2014

Retroviral replicating vector–mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity

Por Hiraoka, Kei, Inagaki, Akihito, Kato, Yuki, Huang, Tiffany T., Mitchell, Leah A., Kamijima, Shuichi, Takahashi, Masamichi, Matsumoto, Hiroshi, Hacke, Katrin, Kruse, Carol A., Ostertag, Derek, Robbins, Joan M., Gruber, Harry E., Jolly, Douglas J., Kasahara, Noriyuki
Publicado no Neuro Oncol (2017)

Design and Selection of Toca 511 for Clinical Use: Modified Retroviral Replicating Vector With Improved Stability and Gene Expression

Por Perez, Omar D, Logg, Christopher R, Hiraoka, Kei, Diago, Oscar, Burnett, Ryan, Inagaki, Akihito, Jolson, Dawn, Amundson, Karin, Buckley, Taylor, Lohse, Dan, Lin, Amy, Burrascano, Cindy, Ibanez, Carlos, Kasahara, Noriyuki, Gruber, Harry E, Jolly, Douglas J
Publicado em 2012

Epithelial Membrane Protein-2 (EMP2) Activates Src Protein and Is a Novel Therapeutic Target for Glioblastoma

Por Qin, Yu, Fu, Maoyong, Takahashi, Masamichi, Iwanami, Akio, Kuga, Daisuke, Rao, Rajiv G., Sudhakar, Deepthi, Huang, Tiffany, Kiyohara, Meagan, Torres, Kathleen, Dillard, Christen, Inagaki, Akihito, Kasahara, Noriyuki, Goodglick, Lee, Braun, Jonathan, Mischel, Paul S., Gordon, Lynn K., Wadehra, Madhuri
Publicado em 2014