Combined Alloreactive CTL Cellular Therapy with Prodrug Activator Gene Therapy in a Model of Breast Cancer Metastatic to the Brain

PURPOSE: Individual or combined strategies of cellular therapy with alloreactive cytotoxic T lymphocytes (alloCTL) and gene therapy employing retroviral replicating vectors (RRV) encoding a suicide prodrug activating gene were explored for the treatment of breast tumors metastatic to the brain. EXPE...

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Main Authors: Hickey, Michelle J., Malone, Colin C., Erickson, Kate L., Lin, Amy, Soto, Horacio, Ha, Edward T., Kamijima, Shuichi, Inagaki, Akihito, Takahashi, Masamichi, Kato, Yuki, Kasahara, Noriyuki, Mueller, Barbara M., Kruse, Carol A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939036/
https://ncbi.nlm.nih.gov/pubmed/23780889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3735
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