Impact of cytochrome P450 2C19 polymorphisms on the pharmacokinetics of tacrolimus when coadministered with voriconazole

por Imamura, Chiyo K., Furihata, Kenichi, Okamoto, Shinichiro, Tanigawara, Yusuke
Publicado no J Clin Pharmacol (2015)

Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12)

por Yoshida, Kayoko, Imamura, Chiyo K., Hara, Kanako, Mochizuki, Mayumi, Tanigawara, Yusuke
Publicado no Metabolomics (2017)

Application of PBPK Modeling and Virtual Clinical Study Approaches to Predict the Outcomes of CYP2D6 Genotype‐Guided Dosing of Tamoxifen

por Nakamura, Toshimichi, Toshimoto, Kota, Lee, Wooin, Imamura, Chiyo K., Tanigawara, Yusuke, Sugiyama, Yuichi
Publicado no CPT Pharmacometrics Syst Pharmacol (2018)

Weekly paclitaxel plus ramucirumab versus weekly nab-paclitaxel plus ramucirumab for unresectable advanced or recurrent gastric cancer with peritoneal dissemination refractory to f...

por Hirata, Kenro, Hamamoto, Yasuo, Ando, Masahiko, Imamura, Chiyo K., Yoshimura, Kenichi, Yamazaki, Kentaro, Hironaka, Shuichi, Muro, Kei
Publicado no BMC Cancer (2020)

Pharmacokinetics, Efficacy and Safety of Bosutinib in a Pediatric Patient With Chronic Myeloid Leukemia

por Inoue, Akiko, Imamura, Chiyo K., Shimada, Hiroyuki, Katayama, Daisuke, Urabe, Keisuke, Suzuki, Ryo, Takitani, Kimitaka, Ashida, Akira
Publicado no J Pediatr Pharmacol Ther (2020)

Sunitinib-induced severe toxicities in a Japanese patient with the ABCG2 421 AA genotype

por Miura, Yuji, Imamura, Chiyo K, Fukunaga, Koya, Katsuyama, Yoshihiko, Suyama, Koichi, Okaneya, Toshikazu, Mushiroda, Taisei, Ando, Yuichi, Takano, Toshimi, Tanigawara, Yusuke
Publicado no BMC Cancer (2014)

Phase I study of afatinib plus bevacizumab in patients with advanced non-squamous non-small cell lung cancer harboring EGFR mutations

por Ko, Ryo, Shukuya, Takehito, Imamura, Chiyo K., Tokito, Takaaki, Shimada, Naoko, Koyama, Ryo, Yamada, Kazuhiko, Ishii, Hidenobu, Azuma, Koichi, Takahashi, Kazuhisa
Publicado no Transl Lung Cancer Res (2021)

The effects of advanced age and serum α(1)‐acid glycoprotein on docetaxel unbound exposure and dose‐limiting toxicity in cancer patients

por Kenmotsu, Hirotsugu, Imamura, Chiyo K., Ono, Akira, Omori, Shota, Nakashima, Kazuhisa, Wakuda, Kazushige, Taira, Tetsuhiko, Naito, Tateaki, Murakami, Haruyasu, Takahashi, Toshiaki, Tanigawara, Yusuke
Publicado no Br J Clin Pharmacol (2017)

A Phase I study of paclitaxel and continuous daily CAI in patients with refractory solid tumors

por Azad, Nilofer, Perroy, Alyssa, Gardner, Erin, Imamura, Chiyo K., Graves, Cynthia, Sarosy, Gisele A., Minasian, Lori, Kotz, Herbert, Raggio, Miranda, Figg, William D., Kohn, Elise C.
Publicado em 2009

Development of an S-1 dosage formula based on renal function by a prospective pharmacokinetic study

por Booka, Eisuke, Imamura, Chiyo K., Takeuchi, Hiroya, Hamamoto, Yasuo, Gomi, Daisuke, Mizukami, Takuro, Ichiyama, Takashi, Tateishi, Kazunari, Takahashi, Tsunehiro, Kawakubo, Hirofumi, Soejima, Kenzo, Boku, Narikazu, Tanigawara, Yusuke, Kitagawa, Yuko
Publicado no Gastric Cancer (2015)

Prospective evaluation and refinement of an S‐1 dosage formula based on renal function for clinical application

por Takeuchi, Masashi, Imamura, Chiyo K., Booka, Eisuke, Takeuchi, Hiroya, Mizukami, Takuro, Kawakami, Takeshi, Funakoshi, Taro, Wakuda, Kazushige, Aoki, Yu, Hamamoto, Yasuo, Kitago, Minoru, Kawakubo, Hirofumi, Boku, Narikazu, Tanigawara, Yusuke, Kitagawa, Yuko
Publicado no Cancer Sci (2021)

CYP2D6 Genotype–Guided Tamoxifen Dosing in Hormone Receptor–Positive Metastatic Breast Cancer (TARGET-1): A Randomized, Open-Label, Phase II Study

por Tamura, Kenji, Imamura, Chiyo K., Takano, Toshimi, Saji, Shigehira, Yamanaka, Takeharu, Yonemori, Kan, Takahashi, Masato, Tsurutani, Junji, Nishimura, Reiki, Sato, Kazuhiko, Kitani, Akira, Ueno, Naoto T., Mushiroda, Taisei, Kubo, Michiaki, Fujiwara, Yasuhiro, Tanigawara, Yusuke
Publicado no J Clin Oncol (2020)

Dynamic changes in CD44v-positive cells after preoperative anti-HER2 therapy and its correlation with pathologic complete response in HER2-positive breast cancer

por Yamauchi, Teruo, Espinosa Fernandez, Jose Rodrigo, Imamura, Chiyo K., Yamauchi, Hideko, Jinno, Hiromitsu, Takahashi, Maiko, Kitagawa, Yuko, Nakamura, Seigo, Lim, Bora, Krishnamurthy, Savitri, Reuben, James M., Liu, Diane, Tripathy, Debasish, Chen, Helen, Takebe, Naoko, Saya, Hideyuki, Ueno, Naoto T.
Publicado no Oncotarget (2018)

A double‐blind, randomized, multicenter phase 3 study of palonosetron vs granisetron combined with dexamethasone and fosaprepitant to prevent chemotherapy‐induced nausea and vomiti...

por Matsumoto, Koji, Takahashi, Masato, Sato, Kazuhiko, Osaki, Akihiko, Takano, Toshimi, Naito, Yoichi, Matsuura, Kazuo, Aogi, Kenjiro, Fujiwara, Kimiko, Tamura, Kenji, Baba, Motoi, Tokunaga, Shinya, Hirano, Gen, Imoto, Shigeru, Miyazaki, Chieko, Yanagihara, Kazuhiro, Imamura, Chiyo K., Chiba, Yasutaka, Saeki, Toshiaki
Publicado no Cancer Med (2020)

Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen Therapy for Breast Cancer Patients

por Kiyotani, Kazuma, Mushiroda, Taisei, Imamura, Chiyo K., Hosono, Naoya, Tsunoda, Tatsuhiko, Kubo, Michiaki, Tanigawara, Yusuke, Flockhart, David A., Desta, Zeruesenay, Skaar, Todd C., Aki, Fuminori, Hirata, Koichi, Takatsuka, Yuichi, Okazaki, Minoru, Ohsumi, Shozo, Yamakawa, Takashi, Sasa, Mitsunori, Nakamura, Yusuke, Zembutsu, Hitoshi
Publicado no J Clin Oncol (2010)

Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non‐small‐cell lung cancer

por Otsubo, Kohei, Nosaki, Kaname, Imamura, Chiyo K., Ogata, Hiroaki, Fujita, Akitaka, Sakata, Shinya, Hirai, Fumihiko, Toyokawa, Gouji, Iwama, Eiji, Harada, Taishi, Seto, Takashi, Takenoyama, Mitsuhiro, Ozeki, Takeshi, Mushiroda, Taisei, Inada, Mieko, Kishimoto, Junji, Tsuchihashi, Kenji, Suina, Kentaro, Nagano, Osamu, Saya, Hideyuki, Nakanishi, Yoichi, Okamoto, Isamu
Publicado no Cancer Sci (2017)

Phase I Trial of the Combination of Flavopiridol and Imatinib Mesylate in Patients with Bcr-Abl(+) Hematological Malignancies

por Bose, Prithviraj, Perkins, Edward B, Honeycut, Connie, Wellons, Martha D, Stefan, Tammy, Jacobberger, James W, Kontopodis, Emmanouil, Beumer, Jan H, Egorin, Merrill J, Imamura, Chiyo K, Figg, W Douglas, Karp, Judith E, Koc, Omer N, Cooper, Brenda W, Luger, Selina M, Colevas, A Dimitrios, Roberts, John D, Grant, Steven
Publicado em 2012

A case report on severe nivolumab-induced adverse events similar to primary sclerosing cholangitis refractory to immunosuppressive therapy

por Hirasawa, Yuya, Yoshimura, Kiyoshi, Matsui, Hiroto, Kubota, Yutaro, Ishida, Hiroo, Arai, Jun, Sakaki, Masashi, Oguro, Nao, Shida, Midori, Taniguchi, Makoto, Hamada, Kazuyuki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Ohkuma, Ryotaro, Sambe, Takehiko, Horiike, Atsushi, Imamura, Chiyo K., Shiozawa, Eisuke, Wada, Satoshi, Tsurutani, Junji, Iwamoto, Sanju, Uchida, Naoki, Kiuchi, Yuji, Tate, Genshu, Kobayashi, Shinichi, Tsunoda, Takuya
Publicado no Medicine (Baltimore) (2021)

Optimizing antiemetic treatment for chemotherapy-induced nausea and vomiting in Japan: Update summary of the 2015  Japan Society of Clinical Oncology Clinical Practice Guidelines f...

por Aogi, Kenjiro, Takeuchi, Hideki, Saeki, Toshiaki, Aiba, Keisuke, Tamura, Kazuo, Iino, Keiko, Imamura, Chiyo K., Okita, Kenji, Kagami, Yoshikazu, Tanaka, Ryuhei, Nakagawa, Kazuhiko, Fujii, Hirofumi, Boku, Narikazu, Wada, Makoto, Akechi, Tatsuo, Iihara, Hirotoshi, Ohtani, Shoichiro, Okuyama, Ayako, Ozawa, Keiko, Kim, Yong-Il, Sasaki, Hidenori, Shima, Yasuo, Takeda, Masayuki, Nagasaki, Eijiro, Nishidate, Toshihiko, Higashi, Takahiro, Hirata, Kouichi
Publicado no Int J Clin Oncol (2020)

The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV

por Akamatsu, Hiroaki, Ninomiya, Kiichiro, Kenmotsu, Hirotsugu, Morise, Masahiro, Daga, Haruko, Goto, Yasushi, Kozuki, Toshiyuki, Miura, Satoru, Sasaki, Takaaki, Tamiya, Akihiro, Teraoka, Shunsuke, Tsubata, Yukari, Yoshioka, Hiroshige, Hattori, Yoshihiro, Imamura, Chiyo K., Katsuya, Yuki, Matsui, Reiko, Minegishi, Yuji, Mizugaki, Hidenori, Nosaki, Kaname, Okuma, Yusuke, Sakamoto, Setsuko, Sone, Takashi, Tanaka, Kentaro, Umemura, Shigeki, Yamanaka, Takeharu, Amano, Shinsuke, Hasegawa, Kazuo, Morita, Satoshi, Nakajima, Kazuko, Maemondo, Makoto, Seto, Takashi, Yamamoto, Nobuyuki
Publicado no Int J Clin Oncol (2019)