Phase I study of salazosulfapyridine in combination with cisplatin and pemetrexed for advanced non‐small‐cell lung cancer

Spliced variant isoforms of CD44 (CD44v) are a marker of cancer stem cells in solid tumors. They stabilize the xCT subunit of the transporter system xc(–) and thereby promote synthesis of the antioxidant glutathione. Salazosulfapyridine (SASP) is an inhibitor of xCT and suppresses the proliferation...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Otsubo, Kohei, Nosaki, Kaname, Imamura, Chiyo K., Ogata, Hiroaki, Fujita, Akitaka, Sakata, Shinya, Hirai, Fumihiko, Toyokawa, Gouji, Iwama, Eiji, Harada, Taishi, Seto, Takashi, Takenoyama, Mitsuhiro, Ozeki, Takeshi, Mushiroda, Taisei, Inada, Mieko, Kishimoto, Junji, Tsuchihashi, Kenji, Suina, Kentaro, Nagano, Osamu, Saya, Hideyuki, Nakanishi, Yoichi, Okamoto, Isamu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581516/
https://ncbi.nlm.nih.gov/pubmed/28667792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13309
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