Decreased Plasma Aβ in Hyperlipidemic APP(SL) Transgenic Mice Is Associated with BBB Dysfunction

Por Löffler, Tina, Flunkert, Stefanie, Temmel, Magdalena, Hutter-Paier, Birgit
Publicado no Front Neurosci (2016)

Non-Selective Calcium Channel Blocker Bepridil Decreases Secondary Pathology in Mice after Photothrombotic Cortical Lesion

Por Lipsanen, Anu, Flunkert, Stefanie, Kuptsova, Kristina, Hiltunen, Mikko, Windisch, Manfred, Hutter-Paier, Birgit, Jolkkonen, Jukka
Publicado em 2013

A Longitudinal Study of Behavioral Deficits in an AβPP Transgenic Mouse Model of Alzheimer’s Disease

Por Havas, Daniel, Hutter-Paier, Birgit, Ubhi, Kiren, Rockenstein, Edward, Crailsheim, Karl, Masliah, Eliezer, Windisch, Manfred
Publicado no J Alzheimers Dis (2011)

Stable Mutated tau441 Transfected SH-SY5Y Cells as Screening Tool for Alzheimer’s Disease Drug Candidates

Por Löffler, Tina, Flunkert, Stefanie, Taub, Nicole, Schofield, Emma L., Ward, Malcolm A., Windisch, Manfred, Hutter-Paier, Birgit
Publicado em 2012

Neuroinflammation and related neuropathologies in APP(SL) mice: further value of this in vivo model of Alzheimer’s disease

Por Löffler, Tina, Flunkert, Stefanie, Havas, Daniel, Schweinzer, Cornelia, Uger, Marni, Windisch, Manfred, Steyrer, Ernst, Hutter-Paier, Birgit
Publicado em 2014

L-type calcium channel blockers and substance P induce angiogenesis of cortical vessels associated with beta-amyloid plaques in an Alzheimer mouse model

Por Daschil, Nina, Kniewallner, Kathrin M., Obermair, Gerald J., Hutter-Paier, Birgit, Windisch, Manfred, Marksteiner, Josef, Humpel, Christian
Publicado no Neurobiol Aging (2015)

Comparison of Pharmacological Modulation of APP Metabolism in Primary Chicken Telencephalic Neurons and in a Human Neuroglioma Cell Line

Por Czvitkovich, Stefan, Duller, Stephan, Mathiesen, Else, Lorenzoni, Klaus, Imbimbo, Bruno P., Hutter-Paier, Birgit, Windisch, Manfred, Wronski, Robert
Publicado em 2010

Ca(V)1.2 Calcium Channel Expression in Reactive Astrocytes is associated with the Formation of Amyloid-β Plaques in an Alzheimer’s Disease Mouse Model

Por Daschil, Nina, Obermair, Gerald J., Flucher, Bernhard E., Stefanova, Nadia, Hutter-Paier, Birgit, Windisch, Manfred, Humpel, Christian, Marksteiner, Josef
Publicado no J Alzheimers Dis (2013)

Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model

Por Amschl David, Neddens Jörg, Havas Daniel, Flunkert Stefanie, Rabl Roland, Römer Heinrich, Rockenstein Edward, Masliah Eliezer, Windisch Manfred, Hutter-Paier Birgit
Publicado em 2013-01-01

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

Por Huttunen, Henri J., Peach, Camilla, Bhattacharyya, Raja, Barren, Cory, Pettingell, Warren, Hutter-Paier, Birgit, Windisch, Manfred, Berezovska, Oksana, Kovacs, Dora M.
Publicado em 2009

Time course and progression of wild type α-Synuclein accumulation in a transgenic mouse model

Por Amschl, David, Neddens, Jörg, Havas, Daniel, Flunkert, Stefanie, Rabl, Roland, Römer, Heinrich, Rockenstein, Edward, Masliah, Eliezer, Windisch, Manfred, Hutter-Paier, Birgit
Publicado em 2013

The Acyl-Coenzyme A:Cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid Pathology in Aged Amyloid Precursor Protein Transgenic Mice

Por Huttunen, Henri J., Havas, Daniel, Peach, Camilla, Barren, Cory, Duller, Stephan, Xia, Weiming, Frosch, Matthew P., Hutter-Paier, Birgit, Windisch, Manfred, Kovacs, Dora M.
Publicado em 2010

Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid

Por Nussbaum, Justin M., Schilling, Stephan, Cynis, Holger, Silva, Antonia, Swanson, Eric, Wangsanut, Tanaporn, Tayler, Kaycie, Wiltgen, Brian, Hatami, Asa, Rönicke, Raik, Reymann, Klaus, Hutter-Paier, Birgit, Alexandru, Anca, Jagla, Wolfgang, Graubner, Sigrid, Glabe, Charles G., Demuth, Hans-Ulrich, Bloom, George S.
Publicado em 2012

Nortriptyline inhibits aggregation and neurotoxicity of alpha-synuclein by enhancing reconfiguration of the monomeric form

Por Collier, Timothy J., Srivastava, Kinshuk R., Justman, Craig, Grammatopoulous, Tom, Hutter-Paier, Birgit, Prokesch, Manuela, Havas, Daniel, Rochet, Jean-Christophe, Liu, Fang, Jock, Kevin, de Oliveira, Patrícia, Stirtz, Georgia L., Dettmer, Ulf, Sortwell, Caryl E., Feany, Mel B., Lansbury, Peter, Lapidus, Lisa, Paumier, Katrina L.
Publicado no Neurobiol Dis (2017)

Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers I: Abeta 42 Oligomer Binding to Specific Neuronal Receptors Is Displaced by Drug Candidates That Improve Cognitive De...

Por Izzo, Nicholas J., Staniszewski, Agnes, To, Lillian, Fa, Mauro, Teich, Andrew F., Saeed, Faisal, Wostein, Harrison, Walko, Thomas, Vaswani, Anisha, Wardius, Meghan, Syed, Zanobia, Ravenscroft, Jessica, Mozzoni, Kelsie, Silky, Colleen, Rehak, Courtney, Yurko, Raymond, Finn, Patricia, Look, Gary, Rishton, Gilbert, Safferstein, Hank, Miller, Miles, Johanson, Conrad, Stopa, Edward, Windisch, Manfred, Hutter-Paier, Birgit, Shamloo, Mehrdad, Arancio, Ottavio, LeVine, Harry, Catalano, Susan M.
Publicado no PLoS One (2014)

Modulation of γ-secretase by EVP-0015962 reduces amyloid deposition and behavioral deficits in Tg2576 mice

Por Rogers, Kathryn, Felsenstein, Kevin M, Hrdlicka, Lori, Tu, Zhiming, Albayya, Faris, Lee, Winnie, Hopp, Sarah, Miller, Mary-Jo, Spaulding, Darcie, Yang, Zhiyong, Hodgdon, Hilliary, Nolan, Scott, Wen, Melody, Costa, Don, Blain, Jean-Francois, Freeman, Emily, De Strooper, Bart, Vulsteke, Veerle, Scrocchi, Louise, Zetterberg, Henrik, Portelius, Erik, Hutter-Paier, Birgit, Havas, Daniel, Ahlijanian, Michael, Flood, Dorothy, Leventhal, Liza, Shapiro, Gideon, Patzke, Holger, Chesworth, Richard, Koenig, Gerhard
Publicado em 2012