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Non-Selective Calcium Channel Blocker Bepridil Decreases Secondary Pathology in Mice after Photothrombotic Cortical Lesion

Experimental studies have identified a complex link between neurodegeneration, β-amyloid (Aβ) and calcium homeostasis. Here we asked whether early phase β-amyloid pathology in transgenic hAPP(SL) mice exaggerates the ischemic lesion and remote secondary pathology in the thalamus, and whether a non-s...

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Detalhes bibliográficos
Main Authors: Lipsanen, Anu, Flunkert, Stefanie, Kuptsova, Kristina, Hiltunen, Mikko, Windisch, Manfred, Hutter-Paier, Birgit, Jolkkonen, Jukka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608597/
https://ncbi.nlm.nih.gov/pubmed/23555933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060235
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