Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats

Alzheimer's disease (AD) and cerebral ischaemia share similar features in terms of altered amyloid precursor protein (APP) processing and β-amyloid (Aβ) accumulation. We have previously shown that Aβ and calcium deposition, and β-secretase activity, are robustly increased in the ipsilateral tha...

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Detalhes bibliográficos
Main Authors: Sarajärvi, Timo, Lipsanen, Anu, Mäkinen, Petra, Peräniemi, Sirpa, Soininen, Hilkka, Haapasalo, Annakaisa, Jolkkonen, Jukka, Hiltunen, Mikko
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118244/
https://ncbi.nlm.nih.gov/pubmed/22805236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2012.01599.x
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