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Protein aggregation and degradation mechanisms in neurodegenerative diseases

Neurodegenerative diseases are characterized by selective neuronal vulnerability and neurodegeneration in specific brain regions. The pathogenesis of these disorders centrally involves abnormal accumulation and aggregation of specific proteins, which are deposited in intracellular inclusions or extr...

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Detalhes bibliográficos
Main Authors: Takalo, Mari, Salminen, Antero, Soininen, Hilkka, Hiltunen, Mikko, Haapasalo, Annakaisa
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601466/
https://ncbi.nlm.nih.gov/pubmed/23516262
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