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Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

Controlled management of protein levels and quality is essential for normal cellular function. Specific molecular chaperones and foldases monitor the levels and assist correct folding of proteins. The ubiquitin-proteasome system recognizes and degrades misfolded proteins that can otherwise be harmfu...

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Bibliografski detalji
Glavni autori: Haapasalo, Annakaisa, Viswanathan, Jayashree, Kurkinen, Kaisa MA, Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P, Tanzi, Rudolph E, Hiltunen, Mikko
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181512/
https://ncbi.nlm.nih.gov/pubmed/21966562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.4.4.15283
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