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Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

Controlled management of protein levels and quality is essential for normal cellular function. Specific molecular chaperones and foldases monitor the levels and assist correct folding of proteins. The ubiquitin-proteasome system recognizes and degrades misfolded proteins that can otherwise be harmfu...

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Main Authors: Haapasalo, Annakaisa, Viswanathan, Jayashree, Kurkinen, Kaisa MA, Bertram, Lars, Soininen, Hilkka, Dantuma, Nico P, Tanzi, Rudolph E, Hiltunen, Mikko
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3181512/
https://ncbi.nlm.nih.gov/pubmed/21966562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.4.4.15283
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