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Protein aggregation and degradation mechanisms in neurodegenerative diseases

Neurodegenerative diseases are characterized by selective neuronal vulnerability and neurodegeneration in specific brain regions. The pathogenesis of these disorders centrally involves abnormal accumulation and aggregation of specific proteins, which are deposited in intracellular inclusions or extr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Takalo, Mari, Salminen, Antero, Soininen, Hilkka, Hiltunen, Mikko, Haapasalo, Annakaisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601466/
https://ncbi.nlm.nih.gov/pubmed/23516262
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