Neuroinflammation and related neuropathologies in APP(SL) mice: further value of this in vivo model of Alzheimer’s disease

BACKGROUND: Beyond cognitive decline, Alzheimer’s disease (AD) is characterized by numerous neuropathological changes in the brain. Although animal models generally do not fully reflect the broad spectrum of disease-specific alterations, the APP(SL) mouse model is well known to display early plaque...

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Detalhes bibliográficos
Main Authors: Löffler, Tina, Flunkert, Stefanie, Havas, Daniel, Schweinzer, Cornelia, Uger, Marni, Windisch, Manfred, Steyrer, Ernst, Hutter-Paier, Birgit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108132/
https://ncbi.nlm.nih.gov/pubmed/24886182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-84
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