Effects of Selective and Non-Selective Glucocorticoid Receptor II Antagonists on Rapid-Onset Diabetes in Young Rats

Por Beaudry, Jacqueline L., Dunford, Emily C., Teich, Trevor, Zaharieva, Dessi, Hunt, Hazel, Belanoff, Joseph K., Riddell, Michael C.
Publicado em 2014

Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double‐Blind, Randomized, Placebo‐Controlled Phase...

Por Hunt, Hazel, Donaldson, Kirsteen, Strem, Mark, Zann, Vanessa, Leung, Pui, Sweet, Suzanne, Connor, Alyson, Combs, Dan, Belanoff, Joseph
Publicado no Clin Pharmacol Drug Dev (2017)

Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction

Por Teich, Trevor, Dunford, Emily C., Porras, Deanna P., Pivovarov, Jacklyn A., Beaudry, Jacqueline L., Hunt, Hazel, Belanoff, Joseph K., Riddell, Michael C.
Publicado no Am J Physiol Endocrinol Metab (2016)

Selection and early clinical evaluation of the brain‐penetrant 11β‐hydroxysteroid dehydrogenase type 1 (11β‐HSD1) inhibitor UE2343 (Xanamem™)

Por Webster, Scott P, McBride, Andrew, Binnie, Margaret, Sooy, Karen, Seckl, Jonathan R, Andrew, Ruth, Pallin, T David, Hunt, Hazel J, Perrior, Trevor R, Ruffles, Vincent S, Ketelbey, J William, Boyd, Alan, Walker, Brian R
Publicado no Br J Pharmacol (2017)

Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator

Por Zalachoras, Ioannis, Houtman, René, Atucha, Erika, Devos, Rene, Tijssen, Ans M. I., Hu, Pu, Lockey, Peter M., Datson, Nicole A., Belanoff, Joseph K., Lucassen, Paul J., Joëls, Marian, de Kloet, E. Ronald, Roozendaal, Benno, Hunt, Hazel, Meijer, Onno C.
Publicado em 2013

Identification of a selective glucocorticoid receptor modulator that prevents both diet‐induced obesity and inflammation

Por van den Heuvel, José K, Boon, Mariëtte R, van Hengel, Ingmar, Peschier‐van der Put, Emma, van Beek, Lianne, van Harmelen, Vanessa, van Dijk, Ko Willems, Pereira, Alberto M, Hunt, Hazel, Belanoff, Joseph K, Rensen, Patrick C N, Meijer, Onno C
Publicado no Br J Pharmacol (2016)

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

Por Vendruscolo, Leandro F., Estey, David, Goodell, Vivian, Macshane, Lauren G., Logrip, Marian L., Schlosburg, Joel E., McGinn, M. Adrienne, Zamora-Martinez, Eva R., Belanoff, Joseph K., Hunt, Hazel J., Sanna, Pietro P., George, Olivier, Koob, George F., Edwards, Scott, Mason, Barbara J.
Publicado no J Clin Invest (2015)

Azepines and Piperidines with Dual Norepinephrine Dopamine Uptake Inhibition and Antidepressant Activity

Por Brown, Dean G., Bernstein, Peter R., Wu, Ye, Urbanek, Rebecca A., Becker, Christopher W., Throner, Scott R., Dembofsky, Bruce T., Steelman, Gary B., Lazor, Lois A., Scott, Clay W., Wood, Michael W., Wesolowski, Steven S., Nugiel, David A., Koch, Stephanie, Yu, Jian, Pivonka, Donald E., Li, Shuang, Thompson, Carol, Zacco, Anna, Elmore, Charles S., Schroeder, Patricia, Liu, JianWei, Hurley, Christopher A., Ward, Stuart, Hunt, Hazel J., Williams, Karen, McLaughlin, Joseph, Hoesch, Valerie, Sydserff, Simon, Maier, Donna, Aharony, David
Publicado em 2012