Identification of a selective glucocorticoid receptor modulator that prevents both diet‐induced obesity and inflammation

BACKGROUND AND PURPOSE: High‐fat diet consumption results in obesity and chronic low‐grade inflammation in adipose tissue. Whereas glucocorticoid receptor (GR) antagonism reduces diet‐induced obesity, GR agonism reduces inflammation, the combination of which would be desired in a strategy to combat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Pharmacol
मुख्य लेखकों: van den Heuvel, José K, Boon, Mariëtte R, van Hengel, Ingmar, Peschier‐van der Put, Emma, van Beek, Lianne, van Harmelen, Vanessa, van Dijk, Ko Willems, Pereira, Alberto M, Hunt, Hazel, Belanoff, Joseph K, Rensen, Patrick C N, Meijer, Onno C
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2016
विषय:
Research Papers
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867737/
https://ncbi.nlm.nih.gov/pubmed/26990179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13477
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