Glucocorticoid antagonism limits adiposity rebound and glucose intolerance in young male rats following the cessation of daily exercise and caloric restriction

Severe caloric restriction (CR), in a setting of regular physical exercise, may be a stress that sets the stage for adiposity rebound and insulin resistance when the food restriction and exercise stop. In this study, we examined the effect of mifepristone, a glucocorticoid (GC) receptor antagonist,...

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Udgivet i:Am J Physiol Endocrinol Metab
Main Authors: Teich, Trevor, Dunford, Emily C., Porras, Deanna P., Pivovarov, Jacklyn A., Beaudry, Jacqueline L., Hunt, Hazel, Belanoff, Joseph K., Riddell, Michael C.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967147/
https://ncbi.nlm.nih.gov/pubmed/27143556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00490.2015
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