Extended haplotype association study in Crohn’s disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3

Por Zhang, Wei, Hui, Ken Y., Gusev, Alexander, Warner, Neil, Evelyn Ng, Sok Meng, Ferguson, John, Choi, Murim, Burberry, Aaron, Abraham, Clara, Mayer, Lloyd, Desnick, Robert J., Cardinale, Christopher J., Hakonarson, Hakon, Waterman, Matti, Chowers, Yehuda, Karban, Amir, Brant, Steven R., Silverberg, Mark S., Gregersen, Peter K., Katz, Seymour, Lifton, Richard P., Zhao, Hongyu, Nuñez, Gabriel, Pe’er, Itsik, Peter, Inga, Cho, Judy H.
Publicado em 2013

Defects in Nicotinamide-adenine Dinucleotide Phosphate Oxidase Genes NOX1 and DUOX2 in Very Early Onset Inflammatory Bowel Disease

Por Hayes, Patti, Dhillon, Sandeep, O’Neill, Kim, Thoeni, Cornelia, Hui, Ken Y., Elkadri, Abdul, Guo, Conghui H., Kovacic, Lidija, Aviello, Gabriella, Alvarez, Luis A., Griffiths, Anne M., Snapper, Scott B., Brant, Steven R., Doroshow, James H., Silverberg, Mark S., Peter, Inga, McGovern, Dermot P.B., Cho, Judy, Brumell, John H., Uhlig, Holm H., Bourke, Billy, Muise, Aleixo M., Knaus, Ulla G.
Publicado no Cell Mol Gastroenterol Hepatol (2015)

Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins

Por Carmi, Shai, Hui, Ken Y., Kochav, Ethan, Liu, Xinmin, Xue, James, Grady, Fillan, Guha, Saurav, Upadhyay, Kinnari, Ben-Avraham, Dan, Mukherjee, Semanti, Bowen, B. Monica, Thomas, Tinu, Vijai, Joseph, Cruts, Marc, Froyen, Guy, Lambrechts, Diether, Plaisance, Stéphane, Van Broeckhoven, Christine, Van Damme, Philip, Van Marck, Herwig, Barzilai, Nir, Darvasi, Ariel, Offit, Kenneth, Bressman, Susan, Ozelius, Laurie J., Peter, Inga, Cho, Judy H., Ostrer, Harry, Atzmon, Gil, Clark, Lorraine N., Lencz, Todd, Pe’er, Itsik
Publicado em 2014

A pleiotropic missense variant in SLC39A8 is associated with Crohn’s disease and human gut microbiome composition

Por Li, Dalin, Achkar, Jean-Paul, Haritunians, Talin, Jacobs, Jonathan P, Hui, Ken Y, D’Amato, Mauro, Brand, Stephan, Radford-Smith, Graham, Halfvarson, Jonas, Niess, Jan-Hendrik, Kugathasan, Subra, Büning, Carsten, Schumm, L Philip, Klei, Lambertus, Ananthakrishnan, Ashwin, Aumais, Guy, Baidoo, Leonard, Dubinsky, Marla, Fiocchi, Claudio, Glas, Jürgen, Milgrom, Raquel, Proctor, Deborah D, Regueiro, Miguel, Simms, Lisa A, Stempak, Joanne M, Targan, Stephan R., Törkvist, Leif, Sharma, Yashoda, Devlin, Bernie, Borneman, James, Hakonarson, Hakon, Xavier, Ramnik J, Daly, Mark, Brant, Steven R, Rioux, John D, Silverberg, Mark S, Cho, Judy H, Braun, Jonathan, McGovern, Dermot PB, Duerr, Richard H
Publicado no Gastroenterology (2016)

A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn’s Disease and Reduces Monocyte Signaling via GMCSF

Por Chuang, Ling-Shiang, Villaverde, Nicole, Hui, Ken Y., Mortha, Arthur, Rahman, Adeeb, Levine, Adam P., Haritunians, Talin, Evelyn Ng, Sok Meng, Zhang, Wei, Hsu, Nai-Yun, Facey, Jody-Ann, Luong, Tramy, Fernandez-Hernandez, Heriberto, Li, Dalin, Rivas, Manuel, Schiff, Elena R., Gusev, Alexander, Schumm, L. Phillip, Bowen, Beatrice M., Sharma, Yashoda, Ning, Kaida, Remark, Romain, Gnjatic, Sacha, Legnani, Peter, George, James, Sands, Bruce E., Stempak, Joanne M., Datta, Lisa W., Lipka, Seth, Katz, Seymour, Cheifetz, Adam S., Barzilai, Nir, Pontikos, Nikolas, Abraham, Clara, Dubinsky, Marla J., Targan, Stephan, Taylor, Kent, Rotter, Jerome I, Scherl, Ellen J., Desnick, Robert J., Abreu, Maria T., Zhao, Hongyu, Atzmon, Gil, Pe’er, Itsik, Kugathasan, Subra, Hakonarson, Hakon, McCauley, Jacob L., Lencz, Todd, Darvasi, Ariel, Plagnol, Vincent, Silverberg, Mark S., Muise, Aleixo M., Brant, Steven R., Daly, Mark J., Segal, Anthony W., Duerr, Richard H., Merad, Miriam, McGovern, Dermot P.B., Peter, Inga, Cho, Judy H.
Publicado no Gastroenterology (2016)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Por Jostins, Luke, Ripke, Stephan, Weersma, Rinse K, Duerr, Richard H, McGovern, Dermot P, Hui, Ken Y, Lee, James C, Schumm, L Philip, Sharma, Yashoda, Anderson, Carl A, Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N, Andersen, Vibeke, Andrews, Jane M, Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A, Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Devaney, Kathy L, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R, Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H, Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C, Lees, Charlie W, Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R, Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y, Potocnik, Uros, Prescott, Natalie J, Regueiro, Miguel, Rotter, Jerome I, Russell, Richard K, Sanderson, Jeremy D, Sans, Miquel, Satsangi, Jack, Schreiber, Stefan, Simms, Lisa A, Sventoraityte, Jurgita, Targan, Stephan R, Taylor, Kent D, Tremelling, Mark, Verspaget, Hein W, De Vos, Martine, Wijmenga, Cisca, Wilson, David C, Winkelmann, Juliane, Xavier, Ramnik J, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K, Zhao, Hongyu, Silverberg, Mark S, Annese, Vito, Hakonarson, Hakon, Brant, Steven R, Radford-Smith, Graham, Mathew, Christopher G, Rioux, John D, Schadt, Eric E, Daly, Mark J, Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C, Cho, Judy H
Publicado em 2012