Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins

The Ashkenazi Jewish (AJ) population is a genetic isolate close to European and Middle Eastern groups, with genetic diversity patterns conducive to disease mapping. Here we report high-depth sequencing of 128 complete genomes of AJ controls. Compared with European samples, our AJ panel has 47% more...

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Main Authors: Carmi, Shai, Hui, Ken Y., Kochav, Ethan, Liu, Xinmin, Xue, James, Grady, Fillan, Guha, Saurav, Upadhyay, Kinnari, Ben-Avraham, Dan, Mukherjee, Semanti, Bowen, B. Monica, Thomas, Tinu, Vijai, Joseph, Cruts, Marc, Froyen, Guy, Lambrechts, Diether, Plaisance, Stéphane, Van Broeckhoven, Christine, Van Damme, Philip, Van Marck, Herwig, Barzilai, Nir, Darvasi, Ariel, Offit, Kenneth, Bressman, Susan, Ozelius, Laurie J., Peter, Inga, Cho, Judy H., Ostrer, Harry, Atzmon, Gil, Clark, Lorraine N., Lencz, Todd, Pe’er, Itsik
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Pub. Group 2014
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164776/
https://ncbi.nlm.nih.gov/pubmed/25203624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5835
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