Are breast cancers driven by fusion genes?

Por Edwards, Paul AW, Howarth, Karen D
Publicado em 2012

The Relative Timing of Mutations in a Breast Cancer Genome

Por Newman, Scott, Howarth, Karen D., Greenman, Chris D., Bignell, Graham R., Tavaré, Simon, Edwards, Paul A. W.
Publicado em 2013

Single-molecule analysis of genome rearrangements in cancer

Por Pole, Jessica C. M., McCaughan, Frank, Newman, Scott, Howarth, Karen D., Dear, Paul H., Edwards, Paul A. W.
Publicado em 2011

Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles

Por Howarth, Karen D., Pole, Jessica C.M., Beavis, Juliet C., Batty, Elizabeth M., Newman, Scott, Bignell, Graham R., Edwards, Paul A.W.
Publicado em 2011

Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes

Por Schulte, Ina, Batty, Elizabeth M, Pole, Jessica CM, Blood, Katherine A, Mo, Steven, Cooke, Susanna L, Ng, Charlotte, Howe, Kevin L, Chin, Suet-Feung, Brenton, James D, Caldas, Carlos, Howarth, Karen D, Edwards, Paul AW
Publicado em 2012

Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone

Por Piccirillo, Sara GM, Spiteri, Inmaculada, Sottoriva, Andrea, Touloumis, Anestis, Ber, Suzan, Price, Stephen J, Heywood, Richard, Francis, Nicola-Jane, Howarth, Karen D, Collins, Vincent P, Venkitaraman, Ashok R, Curtis, Christina, Marioni, John C, Tavaré, Simon, Watts, Colin
Publicado no Cancer Res (2014)

Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling

Por Plagnol, Vincent, Woodhouse, Samuel, Howarth, Karen, Lensing, Stefanie, Smith, Matt, Epstein, Michael, Madi, Mikidache, Smalley, Sarah, Leroy, Catherine, Hinton, Jonathan, de Kievit, Frank, Musgrave-Brown, Esther, Herd, Colin, Baker-Neblett, Katherine, Brennan, Will, Dimitrov, Peter, Campbell, Nathan, Morris, Clive, Rosenfeld, Nitzan, Clark, James, Gale, Davina, Platt, Jamie, Calaway, John, Jones, Greg, Forshew, Tim
Publicado no PLoS One (2018)

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

Por McBride, David J, Etemadmoghadam, Dariush, Cooke, Susanna L, Alsop, Kathryn, George, Joshy, Butler, Adam, Cho, Juok, Galappaththige, Danushka, Greenman, Chris, Howarth, Karen D, Lau, King W, Ng, Charlotte K, Raine, Keiran, Teague, Jon, Wedge, David C, Cancer Study Group, Australian Ovarian, Caubit, Xavier, Stratton, Michael R, Brenton, James D, Campbell, Peter J, Futreal, P Andrew, Bowtell, David DL
Publicado em 2012

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA

Por Gale, Davina, Lawson, Andrew R. J., Howarth, Karen, Madi, Mikidache, Durham, Bradley, Smalley, Sarah, Calaway, John, Blais, Shannon, Jones, Greg, Clark, James, Dimitrov, Peter, Pugh, Michelle, Woodhouse, Samuel, Epstein, Michael, Fernandez-Gonzalez, Ana, Whale, Alexandra S., Huggett, Jim F., Foy, Carole A., Jones, Gerwyn M., Raveh-Amit, Hadas, Schmitt, Karin, Devonshire, Alison, Green, Emma, Forshew, Tim, Plagnol, Vincent, Rosenfeld, Nitzan
Publicado no PLoS One (2018)