The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation

Por Bartelt, Rebekah R., Houtman, Jon C.D.
Publicado em 2012

Functions of the FAK family kinases in T cells: Beyond actin cytoskeletal rearrangement

Por Chapman, Nicole M., Houtman, Jon C.D.
Publicado em 2014

TCR-Mediated Functions Are Enhanced in Activated Peripheral Blood T Cells Isolated From Leucocyte Reduction Systems

Por Tremblay, Mikaela M., Houtman, Jon C.D.
Publicado no J Immunol Methods (2014)

Optimization of Methods for the Genetic Modification of Human T Cells

Por Bilal, Mahmood Y., Vacaflores, Aldo, Houtman, Jon C.D.
Publicado no Immunol Cell Biol (2015)

Prior TLR5 Induction in Human T Cells Results in a Transient Potentiation of Subsequent TCR-Induced Cytokine Production

Por Tremblay, Mikaela M., Bilal, Mahmood Y., Houtman, Jon C.D.
Publicado em 2013

Pretreatment of activated human CD8 T cells with IL-12 leads to enhanced TCR-induced signaling and cytokine production

Por Vacaflores, Aldo, Freedman, Samantha N., Chapman, Nicole M., Houtman, Jon C.D.
Publicado no Mol Immunol (2016)

Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor

Por Chapman, Nicole M., Connolly, Sean F., Reinl, Erin L., Houtman, Jon C.D.
Publicado em 2013

Activated PLC-γ1 is Catalytically Induced at LAT but Activated PLC-γ1 is Localized at both LAT- and TCR-Containing Complexes

Por Cruz-Orcutt, Noemi, Vacaflores, Aldo, Connolly, Sean F., Bunnell, Stephen C., Houtman, Jon C.D.
Publicado em 2014

GADS is Required for TCR-Mediated Calcium Influx and Cytokine Release, but not Cellular Adhesion, in Human T Cells

Por Bilal, Mahmood Y., Zhang, Elizabeth Y., Dinkel, Brittney, Hardy, Daimon, Yankee, Thomas M., Houtman, Jon C.D.
Publicado no Cell Signal (2015)

Regions Outside of Conserved PxxPxR Motifs Drive the High Affinity Interaction of GRB2 with SH3 Domain Ligands

Por Bartelt, Rebekah R., Light, Jonathan, Vacaflores, Aldo, Butcher, Alayna, Pandian, Madhana, Nash, Piers, Houtman, Jon C.D.
Publicado no Biochim Biophys Acta (2015)

Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell...

Por Houtman, Jon C.D., Brown, Patrick H., Bowden, Brent, Yamaguchi, Hiroshi, Appella, Ettore, Samelson, Lawrence E., Schuck, Peter
Publicado em 2007

Glycerol Monolaurate (GML) induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters

Por Zhang, Michael S., Tran, Phuong M., Wolff, Alexander J., Tremblay, Mikaela M., Fosdick, Micaela G., Houtman, Jon C.D.
Publicado no Sci Signal (2018)

Distinct signaling pathways regulate TLR2 co-stimulatory function in human T cells

Por Chapman, Nicole M., Bilal, Mahmood Y., Cruz-Orcutt, Noemi, Knudson, Cory, Madinaveitia, Sofia, Light, Jonathan, Houtman, Jon C.D.
Publicado em 2012

Phosphorylation of Nox1 Regulates Association with NoxA1 Activation Domain

Por Streeter, Jennifer, Schickling, Brandon M., Jiang, Shuxia, Stanic, Bojana, Thiel, William H., Gakhar, Lokesh, Houtman, Jon C.D., Miller, Francis J.
Publicado no Circ Res (2014)

Glycosylation contributes to variability in expression of MCMV m157 and enhances stability of interaction with the NK cell receptor, Ly49H

Por Guseva, Natalya V., Fullenkamp, Colleen A., Naumann, Paul W., Shey, Michael R., Ballas, Zuhair K., Houtman, Jon C.D., Forbes, Catherine A., Scalzo, Anthony A., Heusel, Jonathan W.
Publicado em 2010

NetPath: a public resource of curated signal transduction pathways

Por Kandasamy, Kumaran, Mohan, S Sujatha, Raju, Rajesh, Keerthikumar, Shivakumar, Kumar, Ghantasala S Sameer, Venugopal, Abhilash K, Telikicherla, Deepthi, Navarro, J Daniel, Mathivanan, Suresh, Pecquet, Christian, Gollapudi, Sashi Kanth, Tattikota, Sudhir Gopal, Mohan, Shyam, Padhukasahasram, Hariprasad, Subbannayya, Yashwanth, Goel, Renu, Jacob, Harrys KC, Zhong, Jun, Sekhar, Raja, Nanjappa, Vishalakshi, Balakrishnan, Lavanya, Subbaiah, Roopashree, Ramachandra, YL, Rahiman, B Abdul, Prasad, TS Keshava, Lin, Jian-Xin, Houtman, Jon CD, Desiderio, Stephen, Renauld, Jean-Christophe, Constantinescu, Stefan N, Ohara, Osamu, Hirano, Toshio, Kubo, Masato, Singh, Sujay, Khatri, Purvesh, Draghici, Sorin, Bader, Gary D, Sander, Chris, Leonard, Warren J, Pandey, Akhilesh
Publicado em 2010