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Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor
Focal adhesion kinase (FAK) is a critical regulator of signal transduction in multiple cell types. Although this protein is activated upon T cell receptor (TCR) engagement, the cellular function that FAK plays in mature human T cells is unknown. By suppressing the function of FAK, we revealed that F...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865716/ https://ncbi.nlm.nih.gov/pubmed/24227778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301587 |
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