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Focal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor

Focal adhesion kinase (FAK) is a critical regulator of signal transduction in multiple cell types. Although this protein is activated upon T cell receptor (TCR) engagement, the cellular function that FAK plays in mature human T cells is unknown. By suppressing the function of FAK, we revealed that F...

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書目詳細資料
Main Authors: Chapman, Nicole M., Connolly, Sean F., Reinl, Erin L., Houtman, Jon C.D.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865716/
https://ncbi.nlm.nih.gov/pubmed/24227778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301587
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