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Glycerol Monolaurate (GML) induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters

Glycerol monolaurate (GML) is a monoglyceride with potent antimicrobial properties that suppresses T cell receptor (TCR)-induced signaling and T cell effector function. Actin rearrangement is needed for the interaction of T cells with antigen presenting cells and for migration to sites of infection....

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Pubblicato in:Sci Signal
Autori principali: Zhang, Michael S., Tran, Phuong M., Wolff, Alexander J., Tremblay, Mikaela M., Fosdick, Micaela G., Houtman, Jon C.D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6048963/
https://ncbi.nlm.nih.gov/pubmed/29717064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aam9095
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