Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

by Hoque, Ashfaqul, Williamson, Nicholas A., Ameen, S. Sadia, Ciccotosto, Giuseppe D., Hossain, M. Iqbal, Oakhill, Jonathan S., Ng, Dominic C. H., Ang, Ching-Seng, Cheng, Heung-Chin
Published in Cell Death Dis (2019)

The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2

by Xiao, Min, Xie, Jianling, Wu, Yu, Wang, Genzhu, Qi, Xin, Liu, Zailiang, Wang, Yuying, Wang, Xuemin, Hoque, Ashfaqul, Oakhill, Jon, Proud, Christopher G., Li, Jing
Published in Cell Commun Signal (2020)

Impact of Genetic Variation on Human CaMKK2 Regulation by Ca(2+)-Calmodulin and Multisite Phosphorylation

by O’Brien, Matthew T., Oakhill, Jonathan S., Ling, Naomi X. Y., Langendorf, Christopher G., Hoque, Ashfaqul, Dite, Toby A., Means, Anthony R., Kemp, Bruce E., Scott, John W.
Published in Sci Rep (2017)

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965

by Dite, Toby A., Langendorf, Christopher G., Hoque, Ashfaqul, Galic, Sandra, Rebello, Richard J., Ovens, Ashley J., Lindqvist, Lisa M., Ngoei, Kevin R. W., Ling, Naomi X. Y., Furic, Luc, Kemp, Bruce E., Scott, John W., Oakhill, Jonathan S.
Published in J Biol Chem (2018)

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

by Dite, Toby A., Ling, Naomi X. Y., Scott, John W., Hoque, Ashfaqul, Galic, Sandra, Parker, Benjamin L., Ngoei, Kevin R. W., Langendorf, Christopher G., O’Brien, Matthew T., Kundu, Mondira, Viollet, Benoit, Steinberg, Gregory R., Sakamoto, Kei, Kemp, Bruce E., Oakhill, Jonathan S.
Published in Nat Commun (2017)

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress

by Ling, Naomi X.Y., Kaczmarek, Adrian, Hoque, Ashfaqul, Davie, Elizabeth, Ngoei, Kevin R.W., Morrison, Kaitlin R., Smiles, William J., Forte, Gabriella M., Wang, Tingting, Lie, Shervi, Dite, Toby A., Langendorf, Christopher G., Scott, John W., Oakhill, Jonathan S., Petersen, Janni
Published in Nat Metab (2020)

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

by Langendorf, Christopher G., O'Brien, Matthew T., Ngoei, Kevin R. W., McAloon, Luke M., Dhagat, Urmi, Hoque, Ashfaqul, Ling, Naomi X. Y., Dite, Toby A., Galic, Sandra, Loh, Kim, Parker, Michael W., Oakhill, Jonathan S., Kemp, Bruce E., Scott, John W.
Published in J Biol Chem (2020)

Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells

by Hoque, Ashfaqul, Sivakumaran, Priyadharshini, Bond, Simon T., Ling, Naomi X. Y., Kong, Anne M., Scott, John W., Bandara, Nadeeka, Hernández, Damián, Liu, Guei-Sheung, Wong, Raymond C. B., Ryan, Michael T., Hausenloy, Derek J., Kemp, Bruce E., Oakhill, Jonathan S., Drew, Brian G., Pébay, Alice, Lim, Shiang Y.
Published in Cell Death Discov (2018)

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms

by Pinkosky, Stephen L., Scott, John W., Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ford, Rebecca J., Langendorf, Christopher G., Ling, Naomi X. Y., Nero, Tracy L., Loh, Kim, Galic, Sandra, Hoque, Ashfaqul, Smiles, William J., Ngoei, Kevin R.W., Parker, Michael W., Yan, Yan, Melcher, Karsten, Kemp, Bruce E., Oakhill, Jonathan S., Steinberg, Gregory R.
Published in Nat Metab (2020)