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CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins
The calcium-calmodulin–dependent protein kinase kinase-2 (CaMKK2) is a key regulator of cellular and whole-body energy metabolism. It is known to be activated by increases in intracellular Ca(2+), but the mechanisms by which it is inactivated are less clear. CaMKK2 inhibition protects against prosta...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705300/ https://ncbi.nlm.nih.gov/pubmed/32913128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013756 |
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