AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965

Inhibition of the metabolic regulator AMP-activated protein kinase (AMPK) is increasingly being investigated for its therapeutic potential in diseases where AMPK hyperactivity results in poor prognoses, as in established cancers and neurodegeneration. However, AMPK-inhibitory tool compounds are larg...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Dite, Toby A., Langendorf, Christopher G., Hoque, Ashfaqul, Galic, Sandra, Rebello, Richard J., Ovens, Ashley J., Lindqvist, Lisa M., Ngoei, Kevin R. W., Ling, Naomi X. Y., Furic, Luc, Kemp, Bruce E., Scott, John W., Oakhill, Jonathan S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995511/
https://ncbi.nlm.nih.gov/pubmed/29695504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003547
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