AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965

Inhibition of the metabolic regulator AMP-activated protein kinase (AMPK) is increasingly being investigated for its therapeutic potential in diseases where AMPK hyperactivity results in poor prognoses, as in established cancers and neurodegeneration. However, AMPK-inhibitory tool compounds are larg...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:J Biol Chem
Główni autorzy: Dite, Toby A., Langendorf, Christopher G., Hoque, Ashfaqul, Galic, Sandra, Rebello, Richard J., Ovens, Ashley J., Lindqvist, Lisa M., Ngoei, Kevin R. W., Ling, Naomi X. Y., Furic, Luc, Kemp, Bruce E., Scott, John W., Oakhill, Jonathan S.
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2018
Hasła przedmiotowe:
Signal Transduction
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995511/
https://ncbi.nlm.nih.gov/pubmed/29695504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003547
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