Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death

gan Hoque, Ashfaqul, Williamson, Nicholas A., Ameen, S. Sadia, Ciccotosto, Giuseppe D., Hossain, M. Iqbal, Oakhill, Jonathan S., Ng, Dominic C. H., Ang, Ching-Seng, Cheng, Heung-Chin
Cyhoeddwyd yn Cell Death Dis (2019)

The eEF2 kinase-induced STAT3 inactivation inhibits lung cancer cell proliferation by phosphorylation of PKM2

gan Xiao, Min, Xie, Jianling, Wu, Yu, Wang, Genzhu, Qi, Xin, Liu, Zailiang, Wang, Yuying, Wang, Xuemin, Hoque, Ashfaqul, Oakhill, Jon, Proud, Christopher G., Li, Jing
Cyhoeddwyd yn Cell Commun Signal (2020)

Impact of Genetic Variation on Human CaMKK2 Regulation by Ca(2+)-Calmodulin and Multisite Phosphorylation

gan O’Brien, Matthew T., Oakhill, Jonathan S., Ling, Naomi X. Y., Langendorf, Christopher G., Hoque, Ashfaqul, Dite, Toby A., Means, Anthony R., Kemp, Bruce E., Scott, John W.
Cyhoeddwyd yn Sci Rep (2017)

AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965

gan Dite, Toby A., Langendorf, Christopher G., Hoque, Ashfaqul, Galic, Sandra, Rebello, Richard J., Ovens, Ashley J., Lindqvist, Lisa M., Ngoei, Kevin R. W., Ling, Naomi X. Y., Furic, Luc, Kemp, Bruce E., Scott, John W., Oakhill, Jonathan S.
Cyhoeddwyd yn J Biol Chem (2018)

The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs

gan Dite, Toby A., Ling, Naomi X. Y., Scott, John W., Hoque, Ashfaqul, Galic, Sandra, Parker, Benjamin L., Ngoei, Kevin R. W., Langendorf, Christopher G., O’Brien, Matthew T., Kundu, Mondira, Viollet, Benoit, Steinberg, Gregory R., Sakamoto, Kei, Kemp, Bruce E., Oakhill, Jonathan S.
Cyhoeddwyd yn Nat Commun (2017)

mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress

gan Ling, Naomi X.Y., Kaczmarek, Adrian, Hoque, Ashfaqul, Davie, Elizabeth, Ngoei, Kevin R.W., Morrison, Kaitlin R., Smiles, William J., Forte, Gabriella M., Wang, Tingting, Lie, Shervi, Dite, Toby A., Langendorf, Christopher G., Scott, John W., Oakhill, Jonathan S., Petersen, Janni
Cyhoeddwyd yn Nat Metab (2020)

CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins

gan Langendorf, Christopher G., O'Brien, Matthew T., Ngoei, Kevin R. W., McAloon, Luke M., Dhagat, Urmi, Hoque, Ashfaqul, Ling, Naomi X. Y., Dite, Toby A., Galic, Sandra, Loh, Kim, Parker, Michael W., Oakhill, Jonathan S., Kemp, Bruce E., Scott, John W.
Cyhoeddwyd yn J Biol Chem (2020)

Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells

gan Hoque, Ashfaqul, Sivakumaran, Priyadharshini, Bond, Simon T., Ling, Naomi X. Y., Kong, Anne M., Scott, John W., Bandara, Nadeeka, Hernández, Damián, Liu, Guei-Sheung, Wong, Raymond C. B., Ryan, Michael T., Hausenloy, Derek J., Kemp, Bruce E., Oakhill, Jonathan S., Drew, Brian G., Pébay, Alice, Lim, Shiang Y.
Cyhoeddwyd yn Cell Death Discov (2018)

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms

gan Pinkosky, Stephen L., Scott, John W., Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ford, Rebecca J., Langendorf, Christopher G., Ling, Naomi X. Y., Nero, Tracy L., Loh, Kim, Galic, Sandra, Hoque, Ashfaqul, Smiles, William J., Ngoei, Kevin R.W., Parker, Michael W., Yan, Yan, Melcher, Karsten, Kemp, Bruce E., Oakhill, Jonathan S., Steinberg, Gregory R.
Cyhoeddwyd yn Nat Metab (2020)