Analysis of circulating tumor DNA: The next paradigm shift in detection and treatment of lung cancer

Por Schrump, David S., Hong, Julie A.
Publicado no J Thorac Cardiovasc Surg (2018)

CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells

Por Bu, Xiangning, Kato, Jiro, Hong, Julie A, Merino, Maria J, Schrump, David S, Lund, Frances E, Moss, Joel
Publicado no Carcinogenesis (2018)

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis

Por Xi, Sichuan, Xu, Hong, Shan, Jigui, Tao, Yongguang, Hong, Julie A., Inchauste, Suzanne, Zhang, Mary, Kunst, Tricia F., Mercedes, Leandro, Schrump, David S.
Publicado em 2013

The Pluripotency Factor Musashi-2 Is a Novel Target for Lung Cancer Therapy

Por Zhang, Mary R., Xi, Sichuan, Shukla, Vivek, Hong, Julie A., Chen, Haobin, Xiong, Yin, Ripley, R. Taylor, Hoang, Chuong D., Schrump, David S.
Publicado no Ann Am Thorac Soc (2018)

Cigarette Smoke Induces C/EBP-β-Mediated Activation of miR-31 in Normal Human Respiratory Epithelia and Lung Cancer Cells

Por Xi, Sichuan, Yang, Maocheng, Tao, Yongguang, Xu, Hong, Shan, Jigui, Inchauste, Suzanne, Zhang, Mary, Mercedes, Leandro, Hong, Julie A., Rao, Mahadev, Schrump, David S.
Publicado em 2010

Inhibition of Histone Lysine Methylation Enhances Expression of Cancer-Testis Genes in Lung Cancer Cells: Implications for Adoptive Immunotherapy of Cancer

Por Rao, Mahadev, Chinnasamy, Nachimuthu, Hong, Julie A., Zhang, Yuwei, Zhang, Mary, Xi, Sichuan, Liu, Fang, Marquez, Victor E., Morgan, Richard A., Schrump, David S.
Publicado em 2011

Asbestos Induces Epigenetic Repression of Ras Association Domain–Containing Protein 1, p16 Kinase 4a Inhibitor, and p14 Alternative Reading Frame in Normal Human Mesothelial Cells...

Por Xi, Sichuan, Payabyab, Eden C., Straughan, David M., Reardon, Emily S., Zhang, Mary, Hong, Julie A., Ripley, R. Taylor, Hoang, Chuong D., Schrump, David S.
Publicado no Ann Am Thorac Soc (2018)

Epigenomic Alterations and Gene Expression Profiles in Human Respiratory Epithelial Cells Mediated by Hookah and Cigarette Smoke

Por Xiong, Yin, Xi, Sichuan, Shan, Jigui, Hekimoglu, Elvin, Hsiao, Shih-Hsin, Zhang, Mary, Hong, Julie A., Tao, Chris, Chen, Haobin, Ripley, R. Taylor, Hoang, Chuong D., Schrump, David S.
Publicado no Ann Am Thorac Soc (2018)

De novo Induction of a Cancer/Testis Antigen by 5-Aza-2′-Deoxycytidine Augments Adoptive Immunotherapy in a Murine Tumor Model

Por Guo, Z. Sheng, Hong, Julie A., Irvine, Kari R., Chen, G. Aaron, Spiess, Paul J., Liu, Yang, Zeng, Gang, Wunderlich, John R., Nguyen, Dao M., Restifo, Nicholas P., Schrump, David S.
Publicado em 2006

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

Por Wargo, Jennifer A., Robbins, Paul F., Li, Yong, Zhao, Yangbing, El-Gamil, Mona, Caragacianu, Diana, Zheng, Zhili, Hong, Julie A., Downey, Stephanie, Schrump, David S., Rosenberg, Steven A., Morgan, Richard A.
Publicado em 2008

Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer

Por Cherkasova, Elena, Malinzak, Elizabeth, Rao, Sheila, Takahashi, Yoshiyuki, Senchenko, Vera N., Kudryavtseva, Anna V., Nickerson, Michael L., Merino, Maria, Hong, Julie A., Schrump, David S., Srinivasan, Ramaprasad, Linehan, W. Marston, Tian, Xin, Lerman, Michael I., Childs, Richard W.
Publicado em 2011

Mithramycin Depletes Specificity Protein 1 and Activates p53 to Mediate Senescence and Apoptosis of Malignant Pleural Mesothelioma Cells

Por Rao, Mahadev, Atay, Scott M., Shukla, Vivek, Hong, Young, Upham, Trevor, Ripley, R. Taylor, Hong, Julie A., Zhang, Mary, Reardon, Emily, Fetsch, Patricia, Miettinen, Markku, Li, Xinmin, Peer, Cody J., Sissung, Tristan, Figg, William D., De Rienzo, Assunta, Bueno, Raphael, Schrump, David S.
Publicado no Clin Cancer Res (2015)

Mithramycin Represses Basal and Cigarette Smoke-Induced Expression of ABCG2 and Inhibits Stem Cell Signaling in Lung and Esophageal Cancer Cells

Por Zhang, Mary, Mathur, Aarti, Zhang, Yuwei, Xi, Sichuan, Atay, Scott, Hong, Julie A., Datrice, Nicole, Upham, Trevor, Kemp, Clinton D, Ripley, R. Taylor, Wiegand, Gordon, Avital, Itzak, Fetsch, Patricia, Mani, Haresh, Zlott, Daniel, Robey, Robert, Bates, Susan E., Li, Xinmin, Rao, Mahadev, Schrump, David S.
Publicado no Cancer Res (2012)

Cigarette Smoke Mediates Epigenetic Repression of miR-217 During Esophageal Adenocarcinogenesis

Por Xi, Sichuan, Inchauste, Suzanne, Guo, Hongliang, Shan, Jigui, Xiao, Zuoxiang, Xu, Hong, Miettenen, Markku, Zhang, Mary R., Hong, Julie A., Raiji, Manish T., Altorki, Nasser K., Casson, Alan G, Beer, David G., Robles, Ana I., Bowman, Elise D., Harris, Curtis C., Steinberg, Seth M., Schrump, David S.
Publicado no Oncogene (2015)

Polycomb Repressor Complex-2 is a Novel Target for Mesothelioma Therapy

Por Kemp, Clinton D., Rao, Mahadev, Xi, Sichuan, Inchauste, Suzanne, Mani, Haresh, Fetsch, Patricia, Filie, Armando, Zhang, Mary, Hong, Julie A., Walker, Robert L., Zhu, Yuelin J., Ripley, R.Taylor, Mathur, Aarti, Liu, Fang, Yang, Maocheng, Meltzer, Paul A., Marquez, Victor E., De Rienzo, Assunta, Bueno, Raphael, Schrump, David S.
Publicado no Clin Cancer Res (2011)

Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters

Por Sissung, Tristan M., Huang, Phoebe A., Hauke, Ralph J., McCrea, Edel M., Peer, Cody J., Barbier, Roberto H., Strope, Jonathan D., Ley, Ariel M., Zhang, Mary, Hong, Julie A., Venzon, David, Jackson, Jonathan P., Brouwer, Kenneth R., Grohar, Patrick, Glod, Jon, Widemann, Brigitte C., Heller, Theo, Schrump, David S., Figg, William D.
Publicado no Mol Pharmacol (2019)

UHRF1 is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma

Por Reardon, Emily S., Shukla, Vivek, Xi, Sichuan, Gara, Sudheer K., Liu, Yi, Straughan, David, Zhang, Mary, Hong, Julie A., Payabyab, Eden C., Kumari, Anju, Richards, William G., De Rienzo, Assunta, Hassan, Raffit, Miettinen, Markku, Xi, Liqiang, Raffeld, Mark, Uechi, Lisa T., Li, Xinmin, Wang, Ruihong, Chen, Haobin, Hoang, Chuong D., Bueno, Raphael, Schrump, David S.
Publicado no J Thorac Oncol (2020)

Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model

Por Shukla, Vivek, Rao, Mahadev, Zhang, Hongen, Beers, Jeanette, Wangsa, Darawalee, Wangsa, Danny, Buishand, Floryne O., Wang, Yonghong, Yu, Zhiya, Stevenson, Holly, Reardon, Emily, McLoughlin, Kaitlin C., Kaufman, Andrew, Payabyab, Eden, Hong, Julie A., Zhang, Mary, Davis, Sean R., Edelman, Daniel C., Chen, Guokai, Miettinen, Markku, Restifo, Nicholas, Ried, Thomas, Meltzer, Paul S., Schrump, David S.
Publicado no Ann Am Thorac Soc (2018)

ASXL3 is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer

Por Shukla, Vivek, Rao, Mahadev, Zhang, Hongen, Beers, Jeanette, Wangsa, Darawalee, Wangsa, Danny, Buishand, Floryne O., Wang, Yonghong, Yu, Zhiya, Stevenson, Holly S., Reardon, Emily S., McLoughlin, Kaitlin C., Kaufman, Andrew S., Payabyab, Eden C., Hong, Julie A., Zhang, Mary, Davis, Sean, Edelman, Daniel, Chen, Guokai, Miettinen, Markku M., Restifo, Nicholas P., Ried, Thomas, Meltzer, Paul A., Schrump, David S.
Publicado no Cancer Res (2017)

Telomerase Variant A279T Induces Telomere Dysfunction and Inhibits Non-Canonical Telomerase Activity in Esophageal Carcinomas

Por Zhang, Yuwei, Calado, Rodrigo, Rao, Mahadev, Hong, Julie A., Meeker, Alan K., Dumitriu, Bogdan, Atay, Scott, McCormick, Peter J., Garfield, Susan H., Wangsa, Danny, Padilla-Nash, Hesed M., Burkett, Sandra, Zhang, Mary, Kunst, Tricia F., Peterson, Nathan R., Xi, Sichuan, Inchauste, Suzanne, Altorki, Nasser K., Casson, Alan G., Beer, David G., Harris, Curtis C., Ried, Thomas, Young, Neal S., Schrump, David S.
Publicado em 2014