UHRF1 is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma

OBJECTIVE: Ubiquitin-like with plant homeodomain and ring finger domains 1 (UHRF1) encodes a master regulator of DNA methylation that has emerged as an epigenetic driver in human cancers. To date, no studies have examined UHRF1 in malignant pleural mesothelioma (MPM). The present study was undertake...

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Publicado no:J Thorac Oncol
Main Authors: Reardon, Emily S., Shukla, Vivek, Xi, Sichuan, Gara, Sudheer K., Liu, Yi, Straughan, David, Zhang, Mary, Hong, Julie A., Payabyab, Eden C., Kumari, Anju, Richards, William G., De Rienzo, Assunta, Hassan, Raffit, Miettinen, Markku, Xi, Liqiang, Raffeld, Mark, Uechi, Lisa T., Li, Xinmin, Wang, Ruihong, Chen, Haobin, Hoang, Chuong D., Bueno, Raphael, Schrump, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775915/
https://ncbi.nlm.nih.gov/pubmed/32927122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2020.08.024
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