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Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors

The epidermal growth factor receptor (EGFR) is a promising target for cancer therapy. The presence of certain somatic mutations in the tyrosine kinase (TK) domain of the EGFR gene is associated with clinical response to TK inhibitors (TKI) in patients with lung adenocarcinoma. In this study we evalu...

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Vydáno v:	Oncol Rep
Hlavní autoři:	KALRA, NEETU, ASHAI, ALI, XI, LIQIANG, ZHANG, JINGLI, AVITAL, ITZHAK, RAFFELD, MARK, HASSAN, RAFFIT
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	2012
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6310027/ https://ncbi.nlm.nih.gov/pubmed/22426987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1725
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Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors

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