Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma

BACKGROUND: The development and evaluation of new therapeutic approaches for malignant mesothelioma has been sparse due, in part, to lack of suitable tumor models. METHODS: We established primary mesothelioma cultures from pleural and ascitic fluids of five patients with advanced mesothelioma. Elect...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Kalra, Neetu, Zhang, Jingli, Thomas, Anish, Xi, Liqiang, Cheung, Mitchell, Talarchek, Jacqueline, Burkett, Sandra, Tsokos, Maria G, Chen, Yuanbin, Raffeld, Mark, Miettinen, Markku, Pastan, Ira, Testa, Joseph R, Hassan, Raffit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431029/
https://ncbi.nlm.nih.gov/pubmed/25952750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1362-2
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