Efficacy of Anti-Mesothelin Immunotoxin RG7787 plus nab-Paclitaxel against Mesothelioma Patient Derived Xenografts and Mesothelin as a Biomarker of Tumor Response

PURPOSE: Evaluate anti-tumor efficacy of the reduced immunogenicity anti-mesothelin immunotoxin RG7787 plus nab-Paclitaxel against primary mesothelioma cell lines and tumor xenografts and utility of mesothelin as a biomarker of tumor response. EXPERIMENTAL DESIGN: Early passage human malignant mesot...

Full description

Saved in:
Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Zhang, Jingli, Khanna, Swati, Jiang, Qun, Alewine, Christine, Miettinen, Markku, Pastan, Ira, Hassan, Raffit
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352557/
https://ncbi.nlm.nih.gov/pubmed/27635089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1667
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items