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Patients with peritoneal mesothelioma lack epidermal growth factor receptor tyrosine kinase mutations that would make them sensitive to tyrosine kinase inhibitors

The epidermal growth factor receptor (EGFR) is a promising target for cancer therapy. The presence of certain somatic mutations in the tyrosine kinase (TK) domain of the EGFR gene is associated with clinical response to TK inhibitors (TKI) in patients with lung adenocarcinoma. In this study we evalu...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: KALRA, NEETU, ASHAI, ALI, XI, LIQIANG, ZHANG, JINGLI, AVITAL, ITZHAK, RAFFELD, MARK, HASSAN, RAFFIT
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310027/
https://ncbi.nlm.nih.gov/pubmed/22426987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1725
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