Integrating heterogeneous high-throughput data for meta-dimensional pharmacogenomics and disease-related studies

Por Holzinger, Emily R, Ritchie, Marylyn D
Publicado em 2012

ATHENA: the analysis tool for heritable and environmental network associations

Por Holzinger, Emily R., Dudek, Scott M., Frase, Alex T., Pendergrass, Sarah A., Ritchie, Marylyn D.
Publicado em 2014

ATHENA: A TOOL FOR META-DIMENSIONAL ANALYSIS APPLIED TO GENOTYPES AND GENE EXPRESSION DATA TO PREDICT HDL CHOLESTEROL LEVELS

Por HOLZINGER, EMILY R., DUDEK, SCOTT M., FRASE, ALEX T., KRAUSS, RONALD M., MEDINA, MARISA W., RITCHIE, MARYLYN D.
Publicado em 2013

Initialization Parameter Sweep in ATHENA: Optimizing Neural Networks for Detecting Gene-Gene Interactions in the Presence of Small Main Effects

Por Holzinger, Emily R., Buchanan, Carrie C., Dudek, Scott M., Torstenson, Eric C., Turner, Stephen D., Ritchie, Marylyn D.
Publicado em 2010

Machine learning and data mining in complex genomic data—a review on the lessons learned in Genetic Analysis Workshop 19

Por König, Inke R., Auerbach, Jonathan, Gola, Damian, Held, Elizabeth, Holzinger, Emily R., Legault, Marc-André, Sun, Rui, Tintle, Nathan, Yang, Hsin-Chou
Publicado no BMC Genet (2016)

Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data

Por Holzinger, Emily R., Szymczak, Silke, Malley, James, Pugh, Elizabeth W., Ling, Hua, Griffith, Sean, Zhang, Peng, Li, Qing, Cropp, Cheryl D., Bailey-Wilson, Joan E.
Publicado no BMC Proc (2016)

NEXT-GENERATION ANALYSIS OF CATARACTS: DETERMINING KNOWLEDGE DRIVEN GENE-GENE INTERACTIONS USING BIOFILTER, AND GENE-ENVIRONMENT INTERACTIONS USING THE PHENX TOOLKIT

Por Pendergrass, Sarah A., Verma, Shefali S., Holzinger, Emily R., Moore, Carrie B., Wallace, John, Dudek, Scott M., Huggins, Wayne, Kitchner, Terrie, Waudby, Carol, Berg, Richard, McCarty, Catherine A., Ritchie, Marylyn D.
Publicado em 2013

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

Por Holzinger, Emily R., Grady, Benjamin, Ritchie, Marylyn D., Ribaudo, Heather J., Acosta, Edward P., Morse, Gene D., Gulick, Roy M., Robbins, Gregory K., Clifford, David B., Daar, Eric S., McLaren, Paul, Haas, David W.
Publicado em 2012

Analysis of sequence data to identify potential risk variants for oral clefts in multiplex families

Por Holzinger, Emily R., Li, Qing, Parker, Margaret M., Hetmanski, Jacqueline B., Marazita, Mary L., Mangold, Elisabeth, Ludwig, Kerstin U., Taub, Margaret A., Begum, Ferdouse, Murray, Jeffrey C., Albacha‐Hejazi, Hasan, Alqosayer, Khalid, Al‐Souki, Giath, Albasha Hejazi, Abdullatiff, Scott, Alan F., Beaty, Terri H., Bailey‐Wilson, Joan E.
Publicado no Mol Genet Genomic Med (2017)

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

Por De, Rishika, Verma, Shefali S., Drenos, Fotios, Holzinger, Emily R., Holmes, Michael V., Hall, Molly A., Crosslin, David R., Carrell, David S., Hakonarson, Hakon, Jarvik, Gail, Larson, Eric, Pacheco, Jennifer A., Rasmussen-Torvik, Laura J., Moore, Carrie B., Asselbergs, Folkert W., Moore, Jason H., Ritchie, Marylyn D., Keating, Brendan J., Gilbert-Diamond, Diane
Publicado no BioData Min (2015)

Mitochondrial DNA variation and HIV-associated sensory neuropathy in CHARTER

Por Holzinger, Emily R., Hulgan, Todd, Ellis, Ronald J., Samuels, David C., Ritchie, Marylyn D., Haas, David W., Kallianpur, Asha R., Bloss, Cinnamon S., Clifford, David B., Collier, Ann C., Gelman, Benjamin B., Marra, Christina M., McArthur, Justin C., McCutchan, J. Allen, Morgello, Susan, Simpson, David M., Franklin, Donald R., Rosario, Debralee, Selph, Doug, Letendre, Scott, Grant, Igor
Publicado em 2012

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Por Holzinger, Emily R., Verma, Shefali S., Moore, Carrie B., Hall, Molly, De, Rishika, Gilbert-Diamond, Diane, Lanktree, Matthew B., Pankratz, Nathan, Amuzu, Antoinette, Burt, Amber, Dale, Caroline, Dudek, Scott, Furlong, Clement E., Gaunt, Tom R., Kim, Daniel Seung, Riess, Helene, Sivapalaratnam, Suthesh, Tragante, Vinicius, van Iperen, Erik P.A., Brautbar, Ariel, Carrell, David S., Crosslin, David R., Jarvik, Gail P., Kuivaniemi, Helena, Kullo, Iftikhar J., Larson, Eric B., Rasmussen-Torvik, Laura J., Tromp, Gerard, Baumert, Jens, Cruickshanks, Karen J., Farrall, Martin, Hingorani, Aroon D., Hovingh, G. K., Kleber, Marcus E., Klein, Barbara E., Klein, Ronald, Koenig, Wolfgang, Lange, Leslie A., Mӓrz, Winfried, North, Kari E., Charlotte Onland-Moret, N., Reiner, Alex P., Talmud, Philippa J., van der Schouw, Yvonne T., Wilson, James G., Kivimaki, Mika, Kumari, Meena, Moore, Jason H., Drenos, Fotios, Asselbergs, Folkert W., Keating, Brendan J., Ritchie, Marylyn D.
Publicado no BioData Min (2017)