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Comparison of parametric and machine methods for variable selection in simulated Genetic Analysis Workshop 19 data

Current findings from genetic studies of complex human traits often do not explain a large proportion of the estimated variation of these traits due to genetic factors. This could be, in part, due to overly stringent significance thresholds in traditional statistical methods, such as linear and logi...

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Detalhes bibliográficos
Publicado no:BMC Proc
Main Authors: Holzinger, Emily R., Szymczak, Silke, Malley, James, Pugh, Elizabeth W., Ling, Hua, Griffith, Sean, Zhang, Peng, Li, Qing, Cropp, Cheryl D., Bailey-Wilson, Joan E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133476/
https://ncbi.nlm.nih.gov/pubmed/27980627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-016-0021-1
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