Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the G(q/11) Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simul...

Por Cabana, Jérôme, Holleran, Brian, Leduc, Richard, Escher, Emanuel, Guillemette, Gaétan, Lavigne, Pierre
Publicado no J Biol Chem (2015)

Gα(s) protein binds ubiquitin to regulate epidermal growth factor receptor endosomal sorting

Por Li, Xuezhi, Létourneau, Danny, Holleran, Brian, Leduc, Richard, Lavigne, Pierre, Lavoie, Christine
Publicado no Proc Natl Acad Sci U S A (2017)

Analysis of Transmembrane Domains 1 and 4 of the Human Angiotensin II AT(1) Receptor by Cysteine-scanning Mutagenesis

Por Yan, Liping, Holleran, Brian J., Lavigne, Pierre, Escher, Emanuel, Guillemette, Gaétan, Leduc, Richard
Publicado em 2010

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

Por Holleran, Brian J., Beaulieu, Marie-Eve, Proulx, Christophe D., Lavigne, Pierre, Escher, Emanuel, Leduc, Richard
Publicado em 2007

The Second Transmembrane Domain of the Human Type 1 Angiotensin II Receptor Participates in the Formation of the Ligand Binding Pocket and Undergoes Integral Pivoting Movement du...

Por Domazet, Ivana, Holleran, Brian J., Martin, Stéphane S., Lavigne, Pierre, Leduc, Richard, Escher, Emanuel, Guillemette, Gaétan
Publicado em 2009

Activation Induces Structural Changes in the Liganded Angiotensin II Type 1 Receptor

Por Clément, Martin, Cabana, Jérôme, Holleran, Brian J., Leduc, Richard, Guillemette, Gaétan, Lavigne, Pierre, Escher, Emanuel
Publicado em 2009

Critical Hydrogen Bond Formation for Activation of the Angiotensin II Type 1 Receptor

Por Cabana, Jérôme, Holleran, Brian, Beaulieu, Marie-Ève, Leduc, Richard, Escher, Emanuel, Guillemette, Gaétan, Lavigne, Pierre
Publicado em 2013

The Fifth Transmembrane Domain of Angiotensin II Type 1 Receptor Participates in the Formation of the Ligand-binding Pocket and Undergoes a Counterclockwise Rotation upon Receptor...

Por Domazet, Ivana, Martin, Stéphane S., Holleran, Brian J., Morin, Marie-Ève, Lacasse, Patrick, Lavigne, Pierre, Escher, Emanuel, Leduc, Richard, Guillemette, Gaétan
Publicado em 2009

GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation

Por Tutunea-Fatan, Elena, Abd-Elrahman, Khaled S., Thibodeau, Jean-Francois, Holterman, Chet E., Holleran, Brian J., Leduc, Richard, Kennedy, Christopher R. J., Gros, Robert, Ferguson, Stephen S. G.
Publicado no Sci Rep (2018)