Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata

Por Healey, Kelley R., Perlin, David S.
Publicado no J Fungi (Basel) (2018)

Genetic Drivers of Multidrug Resistance in Candida glabrata

Por Healey, Kelley R., Jimenez Ortigosa, Cristina, Shor, Erika, Perlin, David S.
Publicado no Front Microbiol (2016)

CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction

Por Healey, Kelley R., Katiyar, Santosh K., Raj, Shriya, Edlind, Thomas D.
Publicado em 2012

Sphingolipids Mediate Differential Echinocandin Susceptibility in Candida albicans and Aspergillus nidulans

Por Healey, Kelley R., Challa, Krishna K., Edlind, Thomas D., Katiyar, Santosh K.
Publicado no Antimicrob Agents Chemother (2015)

Candida glabrata Mutants Demonstrating Paradoxical Reduced Caspofungin Susceptibility but Increased Micafungin Susceptibility

Por Healey, Kelley R., Katiyar, Santosh K., Castanheira, Mariana, Pfaller, Michael A., Edlind, Thomas D.
Publicado em 2011

The Gastrointestinal Tract Is a Major Source of Echinocandin Drug Resistance in a Murine Model of Candida glabrata Colonization and Systemic Dissemination

Por Healey, Kelley R., Nagasaki, Yoji, Zimmerman, Matthew, Kordalewska, Milena, Park, Steven, Zhao, Yanan, Perlin, David S.
Publicado no Antimicrob Agents Chemother (2017)

Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility

Por Healey, Kelley R., Kordalewska, Milena, Jiménez Ortigosa, Cristina, Singh, Ashutosh, Berrío, Indira, Chowdhary, Anuradha, Perlin, David S.
Publicado no Antimicrob Agents Chemother (2018)

Fks1 and Fks2 Are Functionally Redundant but Differentially Regulated in Candida glabrata: Implications for Echinocandin Resistance

Por Katiyar, Santosh K., Alastruey-Izquierdo, Ana, Healey, Kelley R., Johnson, Michael E., Perlin, David S., Edlind, Thomas D.
Publicado em 2012

Absence of Azole or Echinocandin Resistance in Candida glabrata Isolates in India despite Background Prevalence of Strains with Defects in the DNA Mismatch Repair Pathway

Por Singh, Ashutosh, Healey, Kelley R., Yadav, Priyanka, Upadhyaya, Gargi, Sachdeva, Neelam, Sarma, Smita, Kumar, Anil, Tarai, Bansidhar, Perlin, David S., Chowdhary, Anuradha
Publicado no Antimicrob Agents Chemother (2018)

Molecular Analysis of Resistance and Detection of Non-Wild-Type Strains Using Etest Epidemiological Cutoff Values for Amphotericin B and Echinocandins for Bloodstream Candida Infec...

Por Taj-Aldeen, Saad J., Salah, Husam, Perez, Winder B., Almaslamani, Muna, Motyl, Mary, AbdulWahab, Atqah, Healey, Kelley R., Perlin, David S.
Publicado no Antimicrob Agents Chemother (2018)

Multilocus Sequence Typing (MLST) Genotypes of Candida glabrata Bloodstream Isolates in Korea: Association With Antifungal Resistance, Mutations in Mismatch Repair Gene (Msh2), and...

Por Byun, Seung A., Won, Eun Jeong, Kim, Mi-Na, Lee, Wee Gyo, Lee, Kyungwon, Lee, Hye Soo, Uh, Young, Healey, Kelley R., Perlin, David S., Choi, Min Ji, Kim, Soo Hyun, Shin, Jong Hee
Publicado no Front Microbiol (2018)

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance

Por Healey, Kelley R., Zhao, Yanan, Perez, Winder B., Lockhart, Shawn R., Sobel, Jack D., Farmakiotis, Dimitrios, Kontoyiannis, Dimitrios P., Sanglard, Dominique, Taj-Aldeen, Saad J., Alexander, Barbara D., Jimenez-Ortigosa, Cristina, Shor, Erika, Perlin, David S.
Publicado no Nat Commun (2016)

VT-1598 inhibits the in vitro growth of mucosal Candida strains and protects against fluconazole-susceptible and -resistant oral candidiasis in IL-17 signalling-deficient mice

Por Break, Timothy J, Desai, Jigar V, Healey, Kelley R, Natarajan, Mukil, Ferre, Elise M N, Henderson, Christina, Zelazny, Adrian, Siebenlist, Ulrich, Yates, Christopher M, Cohen, Oren J, Schotzinger, Robert J, Perlin, David S, Garvey, Edward P, Lionakis, Michail S
Publicado no J Antimicrob Chemother (2018)