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Sphingolipids Mediate Differential Echinocandin Susceptibility in Candida albicans and Aspergillus nidulans

The cell wall synthesis-inhibiting echinocandins, including caspofungin and micafungin, play important roles in the treatment of candidiasis and aspergillosis. Previous studies revealed that, in the haploid yeast Candida glabrata, sphingolipid biosynthesis pathway mutations confer caspofungin reduce...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Healey, Kelley R., Challa, Krishna K., Edlind, Thomas D., Katiyar, Santosh K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432167/
https://ncbi.nlm.nih.gov/pubmed/25824222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04667-14
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