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Sphingolipids Mediate Differential Echinocandin Susceptibility in Candida albicans and Aspergillus nidulans

The cell wall synthesis-inhibiting echinocandins, including caspofungin and micafungin, play important roles in the treatment of candidiasis and aspergillosis. Previous studies revealed that, in the haploid yeast Candida glabrata, sphingolipid biosynthesis pathway mutations confer caspofungin reduce...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Healey, Kelley R., Challa, Krishna K., Edlind, Thomas D., Katiyar, Santosh K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432167/
https://ncbi.nlm.nih.gov/pubmed/25824222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04667-14
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