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Sphingolipids Mediate Differential Echinocandin Susceptibility in Candida albicans and Aspergillus nidulans

The cell wall synthesis-inhibiting echinocandins, including caspofungin and micafungin, play important roles in the treatment of candidiasis and aspergillosis. Previous studies revealed that, in the haploid yeast Candida glabrata, sphingolipid biosynthesis pathway mutations confer caspofungin reduce...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Healey, Kelley R., Challa, Krishna K., Edlind, Thomas D., Katiyar, Santosh K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432167/
https://ncbi.nlm.nih.gov/pubmed/25824222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04667-14
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