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CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction

Infections with the azole-refractory yeast Candida glabrata are now commonly treated with the echinocandins caspofungin (CSF) or micafungin (MCF). True resistance (>32-fold decreased susceptibility) to these lipopeptide inhibitors of cell wall synthesis is rare and strictly associated with mutati...

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Detalhes bibliográficos
Main Authors: Healey, Kelley R., Katiyar, Santosh K., Raj, Shriya, Edlind, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472958/
https://ncbi.nlm.nih.gov/pubmed/22909030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08194.x
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