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Polymorphism of Polymeric Amino Acid Regions in Fungal Proteins and Correlation with Altered Echinocandin and Azole Susceptibility

Polymorphism of polymeric amino acid (polyX) regions within fungal proteins represents a potential mechanism for rapid genotypic adaptation to environmental pressures, including antifungal exposure. Polyglutamine (polyQ) was the most abundant repeat in the proteomes of 8 diverse fungal species and w...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Challa, Krishna, Edlind, Tom, Katiyar, Santosh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256777/
https://ncbi.nlm.nih.gov/pubmed/30297363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00870-18
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