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New Fks Hot Spot for Acquired Echinocandin Resistance in Saccharomyces cerevisiae and Its Contribution to Intrinsic Resistance of Scedosporium Species

Echinocandins represent a new antifungal group with potent activity against Candida species. These lipopeptides inhibit the synthesis of β-1,3-glucan, the major cell wall polysaccharide. Acquired resistance or reduced echinocandin susceptibility (RES) is rare and associated with mutations in two “ho...

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Detalhes bibliográficos
Main Authors: Johnson, Michael E., Katiyar, Santosh K., Edlind, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147641/
https://ncbi.nlm.nih.gov/pubmed/21576441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01811-10
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