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Sphingolipids Mediate Differential Echinocandin Susceptibility in Candida albicans and Aspergillus nidulans

The cell wall synthesis-inhibiting echinocandins, including caspofungin and micafungin, play important roles in the treatment of candidiasis and aspergillosis. Previous studies revealed that, in the haploid yeast Candida glabrata, sphingolipid biosynthesis pathway mutations confer caspofungin reduce...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Healey, Kelley R., Challa, Krishna K., Edlind, Thomas D., Katiyar, Santosh K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432167/
https://ncbi.nlm.nih.gov/pubmed/25824222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04667-14
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