Overproduction of a M(r) 92,000 protomer of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in compactin-resistant C100 cells

Por Hardeman, Edna C., Jenke, Hans-Stephan, Simoni, Robert D.
Publicado em 1983

Lighting up microtubule cytoskeleton dynamics in skeletal muscle

Por Masedunskas, Andrius, Appaduray, Mark, Gunning, Peter W, Hardeman, Edna C
Publicado no Intravital (2014)

SUMOylation of GTF2IRD1 Regulates Protein Partner Interactions and Ubiquitin-Mediated Degradation

Por Widagdo, Jocelyn, Taylor, Kylie M., Gunning, Peter W., Hardeman, Edna C., Palmer, Stephen J.
Publicado em 2012

Modulating myosin restores muscle function in a mouse model of nemaline myopathy

Por Lindqvist, Johan, Levy, Yotam, Pati‐Alam, Alisha, Hardeman, Edna C., Gregorevic, Paul, Ochala, Julien
Publicado no Ann Neurol (2016)

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain

Por Suchowerska, Alexandra K., Fok, Sandra, Stefen, Holly, Gunning, Peter W., Hardeman, Edna C., Power, John, Fath, Thomas
Publicado no Front Cell Neurosci (2017)

Tropomyosin Promotes Lamellipodial Persistence by Collaborating with Arp2/3 at the Leading Edge

Por Brayford, Simon, Bryce, Nicole S., Schevzov, Galina, Haynes, Elizabeth M., Bear, James E., Hardeman, Edna C., Gunning, Peter W.
Publicado no Curr Biol (2016)

Regulation of alternative splicing of Gtf2ird1 and its impact on slow muscle promoter activity.

Por Tay, Enoch S E, Guven, Kim L, Subramaniam, Nanthakumar, Polly, Patsie, Issa, Laura L, Gunning, Peter W, Hardeman, Edna C
Publicado em 2003

The role of GTF2IRD1 in the auditory pathology of Williams–Beuren Syndrome

Por Canales, Cesar P, Wong, Ann C Y, Gunning, Peter W, Housley, Gary D, Hardeman, Edna C, Palmer, Stephen J
Publicado no Eur J Hum Genet (2015)

Skeletal muscle repair in a mouse model of nemaline myopathy

Por Sanoudou, Despina, Corbett, Mark A., Han, Mei, Ghoddusi, Majid, Nguyen, Mai-Anh T., Vlahovich, Nicole, Hardeman, Edna C., Beggs, Alan H.
Publicado em 2006

Identification of a Novel Slow-Muscle-Fiber Enhancer Binding Protein, MusTRD1

Por O'Mahoney, John V., guven, Kim L., Lin, Jia, Joya, Josephine E., Robinson, C. Stephen, Wade, Robert P., Hardeman, Edna C.
Publicado em 2000

Identification of a Novel Slow-Muscle-Fiber Enhancer Binding Protein, MusTRD1

Por O’Mahoney, John V., Guven, Kim L., Lin, Jia, Joya, Josephine E., Robinson, C. Stephen, Wade, Robert P., Hardeman, Edna C.
Publicado em 1998

Transcription occurs in pulses in muscle fibers

Por Newlands, Sarah, Levitt, Linda K., Robinson, C. Stephen, Karpf, A.B. Carmen, Hodgson, Vanessa R.M., Wade, Robert P., Hardeman, Edna C.
Publicado em 1998

Combined MRI and (31)P-MRS Investigations of the ACTA1(H40Y) Mouse Model of Nemaline Myopathy Show Impaired Muscle Function and Altered Energy Metabolism

Por Gineste, Charlotte, Le Fur, Yann, Vilmen, Christophe, Le Troter, Arnaud, Pecchi, Emilie, Cozzone, Patrick J., Hardeman, Edna C., Bendahan, David, Gondin, Julien
Publicado em 2013

RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome

Por Corley, Susan M., Canales, Cesar P., Carmona-Mora, Paulina, Mendoza-Reinosa, Veronica, Beverdam, Annemiek, Hardeman, Edna C., Wilkins, Marc R., Palmer, Stephen J.
Publicado no BMC Genomics (2016)

Aged skeletal muscle retains the ability to fully regenerate functional architecture

Por Lee, Antonio S.J., Anderson, Judy E., Joya, Josephine E., Head, Stewart I., Pather, Nalini, Kee, Anthony J., Gunning, Peter W., Hardeman, Edna C.
Publicado em 2013

Recruitment Kinetics of Tropomyosin Tpm3.1 to Actin Filament Bundles in the Cytoskeleton Is Independent of Actin Filament Kinetics

Por Appaduray, Mark A., Masedunskas, Andrius, Bryce, Nicole S., Lucas, Christine A., Warren, Sean C., Timpson, Paul, Stear, Jeffrey H., Gunning, Peter W., Hardeman, Edna C.
Publicado no PLoS One (2016)

GTF2IRD2 from the Williams–Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members

Por Palmer, Stephen J., Taylor, Kylie M., Santucci, Nicole, Widagdo, Jocelyn, Chan, Yee-Ka Agnes, Yeo, Jen-Li, Adams, Merritt, Gunning, Peter W., Hardeman, Edna C.
Publicado em 2012

Alterations at the Cross-Bridge Level Are Associated with a Paradoxical Gain of Muscle Function In Vivo in a Mouse Model of Nemaline Myopathy

Por Gineste, Charlotte, Ottenheijm, Coen, Le Fur, Yann, Banzet, Sébastien, Pecchi, Emilie, Vilmen, Christophe, Cozzone, Patrick J., Koulmann, Nathalie, Hardeman, Edna C., Bendahan, David, Gondin, Julien
Publicado em 2014

Negative Autoregulation of GTF2IRD1 in Williams-Beuren Syndrome via a Novel DNA Binding Mechanism

Por Palmer, Stephen J., Santucci, Nicole, Widagdo, Jocelyn, Bontempo, Sara J., Taylor, Kylie M., Tay, Enoch S. E., Hook, Jeff, Lemckert, Frances, Gunning, Peter W., Hardeman, Edna C.
Publicado em 2010

Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

Por Vlahovich, Nicole, Kee, Anthony J., Van der Poel, Chris, Kettle, Emma, Hernandez-Deviez, Delia, Lucas, Christine, Lynch, Gordon S., Parton, Robert G., Gunning, Peter W., Hardeman, Edna C.
Publicado em 2009