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SUMOylation of GTF2IRD1 Regulates Protein Partner Interactions and Ubiquitin-Mediated Degradation

GTF2IRD1 is one of the genes implicated in Williams-Beuren syndrome, a disease caused by haploinsufficiency of certain dosage-sensitive genes within a hemizygous microdeletion of chromosome 7. GTF2IRD1 is a prime candidate for some of the major features of the disease, presumably caused by abnormall...

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Main Authors: Widagdo, Jocelyn, Taylor, Kylie M., Gunning, Peter W., Hardeman, Edna C., Palmer, Stephen J.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493543/
https://ncbi.nlm.nih.gov/pubmed/23145142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049283
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