Alterations at the Cross-Bridge Level Are Associated with a Paradoxical Gain of Muscle Function In Vivo in a Mouse Model of Nemaline Myopathy

Nemaline myopathy is the most common disease entity among non-dystrophic skeletal muscle congenital diseases. The first disease causing mutation (Met9Arg) was identified in the gene encoding α-tropomyosin(slow) gene (TPM3). Considering the conflicting findings of the previous studies on the transgen...

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Detalhes bibliográficos
Main Authors: Gineste, Charlotte, Ottenheijm, Coen, Le Fur, Yann, Banzet, Sébastien, Pecchi, Emilie, Vilmen, Christophe, Cozzone, Patrick J., Koulmann, Nathalie, Hardeman, Edna C., Bendahan, David, Gondin, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182639/
https://ncbi.nlm.nih.gov/pubmed/25268244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109066
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