Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

Por Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
Publicado no ACS Med Chem Lett (2015)

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Por Ren, Chunyan, Zhang, Guangtao, Han, Fangbin, Fu, Shibo, Cao, Yingdi, Zhang, Fan, Zhang, Qiang, Meslamani, Jamel, Xu, Yaoyao, Ji, Donglei, Cao, Lingling, Zhou, Qian, Cheung, Ka-lung, Sharma, Rajal, Babault, Nicolas, Yi, Zhengzi, Zhang, Weijia, Walsh, Martin J., Zeng, Lei, Zhou, Ming-Ming
Publicado no Proc Natl Acad Sci U S A (2018)

Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors

Por Wang, Yonghui, Cai, Wei, Cheng, Yaobang, Yang, Ting, Liu, Qian, Zhang, Guifeng, Meng, Qinghua, Han, Fangbin, Huang, Yafei, Zhou, Ling, Xiang, Zhijun, Zhao, Yong-Gang, Xu, Yan, Cheng, Ziqiang, Lu, Sijie, Wu, Qianqian, Xiang, Jia-Ning, Elliott, John D., Leung, Stewart, Ren, Feng, Lin, Xichen
Publicado no ACS Med Chem Lett (2015)