Mirk kinase inhibition blocks the in vivo growth of pancreatic cancer cells

Por Deng, Xiaobing, Friedman, Eileen
Publicado em 2014

Mirk/Dyrk1B Maintains the Viability of Quiescent Pancreatic Cancer Cells by Reducing Levels of Reactive Oxygen Species

Por Deng, Xiaobing, Ewton, Daina Z., Friedman, Eileen
Publicado em 2009

Mirk/dyrk1B kinase is upregulated following inhibition of mTOR

Por Deng, Xiaobing, Hu, Jing, Ewton, Daina Z., Friedman, Eileen
Publicado em 2014

Mirk kinase inhibition targets ovarian cancer ascites

Por Deng, Xiaobing, Hu, Jing, Cunningham, Mary J., Friedman, Eileen
Publicado em 2014

The normal function of the cancer kinase Mirk/dyrk1B is to reduce reactive oxygen species

Por Deng, Xiaobing, Mercer, Stephen E., Sun, Chi-Yu, Friedman, Eileen
Publicado em 2014

A novel allosteric inhibitor that prevents IKKβ activation

Por Liu, Hongbo, Liang, Hao, Meng, Hu, Deng, Xiaobing, Zhang, Xiaoling, Lai, Luhua
Publicado no Medchemcomm (2018)

Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

Por Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Publicado no Front Chem (2018)

Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy

Por Li, Cong, Deng, Xiaobing, Xie, Xiaowen, Liu, Ying, Friedmann Angeli, José Pedro, Lai, Luhua
Publicado no Front Pharmacol (2018)

MIRK/DYRK1B MEDIATES SURVIVAL DURING THE DIFFERENTIATION OF C2C12 MYOBLASTS

Por Mercer, Stephen E., Ewton, Daina Z., Deng, Xiaobing, Lim, Seunghwan, Mazur, Thomas R., Friedman, Eileen
Publicado em 2005

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

Por Han, Fangbin, Lin, Songwen, Liu, Peng, Liu, Xiujie, Tao, Jing, Deng, Xiaobing, Yi, Chongqin, Xu, Heng
Publicado no ACS Med Chem Lett (2015)

Rational design of selective allosteric inhibitors of PHDGH and serine synthesis with in vivo activity

Por Wang, Qian, Liberti, Maria V., Liu, Pei, Deng, Xiaobing, Liu, Ying, Locasale, Jason W., Lai, Luhua
Publicado no Cell Chem Biol (2016)

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

Por Liu, Pei, Liu, Hongbo, Sun, Qi, Liang, Hao, Li, Chunmei, Deng, Xiaobing, Liu, Ying, Lai, Luhua
Publicado no Eur J Med Chem (2020)

The Ets protein Pointed prevents both premature differentiation and dedifferentiation of Drosophila intermediate neural progenitors

Por Xie, Yonggang, Li, Xiaosu, Deng, Xiaobing, Hou, Yanjun, O'Hara, Krysten, Urso, Andreacarola, Peng, Ying, Chen, Li, Zhu, Sijun
Publicado no Development (2016)

Inactivation of Mirk/Dyrk1b Kinase Targets Quiescent Pancreatic Cancer Cells

Por Ewton, Daina Z., Hu, Jing, Vilenchik, Maria, Deng, Xiaobing, Luk, Kin-chun, Polonskaia, Ann, Hoffman, Ann F., Zipf, Karen, Boylan, John F., Friedman, Eileen A.
Publicado em 2011