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Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds
SARS-CoV-2 3C-like protease is the main protease of SARS-CoV-2 and has been considered as one of the key targets for drug discovery against COVID-19. We identified several N-substituted isatin compounds as potent SARS-CoV-2 3C-like protease inhibitors. The three most potent compounds inhibit SARS-Co...
Tallennettuna:
| Julkaisussa: | Eur J Med Chem |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Elsevier Masson SAS.
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7395831/ https://ncbi.nlm.nih.gov/pubmed/32798789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112702 |
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