Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors

Tumor necrosis factor-α (TNF-α) plays a pivotal role in inflammatory response. Dysregulation of TNF can lead to a variety of disastrous pathological effects, including auto-inflammatory diseases. Antibodies that directly targeting TNF-α have been proven effective in suppressing symptoms of these dis...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Deng, Xiaobing, Zhang, Xiaoling, Tang, Bo, Liu, Hongbo, Shen, Qi, Liu, Ying, Lai, Luhua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893771/
https://ncbi.nlm.nih.gov/pubmed/29670876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00098
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados