Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies

por Loughran, Stephen, Haas, Simon, Wilkinson, Adam C., Klein, Allon, Brand, Marjorie
Publicado en Exp Hematol (2020)

Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses

por Ketzer, Patrick, Haas, Simon F., Engelhardt, Sarah, Hartig, Jörg S., Nettelbeck, Dirk M.
Publicado 2012

IFNα-mediated remodeling of endothelial cells in the bone marrow niche

por Prendergast, Áine M., Kuck, Andrea, van Essen, Mieke, Haas, Simon, Blaszkiewicz, Sandra, Essers, Marieke A. G.
Publicado en Haematologica (2017)

Technical Considerations for the Use of CRISPR/Cas9 in Hematology Research

por Gundry, Michael C., Dever, Daniel P., Yudovich, David, Bauer, Daniel E., Haas, Simon, Wilkinson, Adam C., Singbrant, Sofie
Publicado en Exp Hematol (2017)

Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4

por Uckelmann, Hannah, Blaszkiewicz, Sandra, Nicolae, Claudia, Haas, Simon, Schnell, Alexandra, Wurzer, Stephan, Wagener, Raimund, Aszodi, Attila, Essers, Marieke Alida Gertruda
Publicado en J Exp Med (2016)

Single-cell lineage tracing approaches in hematology research — technical considerations

por Carrelha, Joana, Lin, Dawn S., Rodriguez-Fraticelli, Alejo E., Luis, Tiago C., Wilkinson, Adam C, Cabezas-Wallscheid, Nina, Tremblay, Cedric S., Haas, Simon
Publicado en Exp Hematol (2020)

Combined single-cell and spatial transcriptomics reveals the molecular, cellular and spatial bone marrow niche organization

por Baccin, Chiara, Al-Sabah, Jude, Velten, Lars, Helbling, Patrick M., Grünschläger, Florian, Hernández-Malmierca, Pablo, Nombela-Arrieta, César, Steinmetz, Lars M., Trumpp, Andreas, Haas, Simon
Publicado en Nat Cell Biol (2020)

Braveheart, a long non-coding RNA required for cardiovascular lineage commitment

por Klattenhoff, Carla, Scheuermann, Johanna C., Surface, Lauren E., Bradley, Robert K., Fields, Paul A., Steinhauser, Matthew L., Ding, Huiming, Butty, Vincent L., Torrey, Lillian, Haas, Simon, Abo, Ryan, Tabebordbar, Mohammadsharif, Lee, Richard T., Burge, Christopher B., Boyer, Laurie A.
Publicado 2013

Human haematopoietic stem cell lineage commitment is a continuous process

por Velten, Lars, Haas, Simon F., Raffel, Simon, Blaszkiewicz, Sandra, Islam, Saiful, Hennig, Bianca P., Hirche, Christoph, Lutz, Christoph, Buss, Eike C., Nowak, Daniel, Boch, Tobias, Hofmann, Wolf-Karsten, Ho, Anthony D., Huber, Wolfgang, Trumpp, Andreas, Essers, Marieke A.G., Steinmetz, Lars M.
Publicado en Nat Cell Biol (2017)

Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite sequencing

por Lipka, Daniel B, Wang, Qi, Cabezas-Wallscheid, Nina, Klimmeck, Daniel, Weichenhan, Dieter, Herrmann, Carl, Lier, Amelie, Brocks, David, von Paleske, Lisa, Renders, Simon, Wünsche, Peer, Zeisberger, Petra, Gu, Lei, Haas, Simon, Essers, Marieke Ag, Brors, Benedikt, Eils, Roland, Trumpp, Andreas, Milsom, Michael D, Plass, Christoph
Publicado en Cell Cycle (2014)

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics

por Velten, Lars, Story, Benjamin A., Hernández-Malmierca, Pablo, Raffel, Simon, Leonce, Daniel R., Milbank, Jennifer, Paulsen, Malte, Demir, Aykut, Szu-Tu, Chelsea, Frömel, Robert, Lutz, Christoph, Nowak, Daniel, Jann, Johann-Christoph, Pabst, Caroline, Boch, Tobias, Hofmann, Wolf-Karsten, Müller-Tidow, Carsten, Trumpp, Andreas, Haas, Simon, Steinmetz, Lars M.
Publicado en Nat Commun (2021)

Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause

por Scognamiglio, Roberta, Cabezas-Wallscheid, Nina, Thier, Marc Christian, Altamura, Sandro, Reyes, Alejandro, Prendergast, Áine M., Baumgärtner, Daniel, Carnevalli, Larissa S., Atzberger, Ann, Haas, Simon, von Paleske, Lisa, Boroviak, Thorsten, Wörsdörfer, Philipp, Essers, Marieke A.G., Kloz, Ulrich, Eisenman, Robert N., Edenhofer, Frank, Bertone, Paul, Huber, Wolfgang, van der Hoeven, Franciscus, Smith, Austin, Trumpp, Andreas
Publicado en Cell (2016)

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

por Lutsik, Pavlo, Baude, Annika, Mancarella, Daniela, Öz, Simin, Kühn, Alexander, Toth, Reka, Hey, Joschka, Toprak, Umut H., Lim, Jinyeong, Nguyen, Viet Ha, Jiang, Chao, Mayakonda, Anand, Hartmann, Mark, Rosemann, Felix, Breuer, Kersten, Vonficht, Dominik, Grünschläger, Florian, Lee, Suman, Schuhmacher, Maren Kirstin, Kusevic, Denis, Jauch, Anna, Weichenhan, Dieter, Zustin, Jozef, Schlesner, Matthias, Haas, Simon, Park, Joo Hyun, Park, Yoon Jung, Oppermann, Udo, Jeltsch, Albert, Haller, Florian, Fellenberg, Jörg, Lindroth, Anders M., Plass, Christoph
Publicado en Nat Commun (2020)

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats

por Brocks, David, Schmidt, Christopher R., Daskalakis, Michael, Jang, Hyo Sik, Shah, Nakul M., Li, Daofeng, Li, Jing, Zhang, Bo, Hou, Yiran, Laudato, Sara, Lipka, Daniel B., Schott, Johanna, Bierhoff, Holger, Assenov, Yassen, Helf, Monika, Ressnerova, Alzbeta, Islam, Md Saiful, Lindroth, Anders M., Haas, Simon, Essers, Marieke, Imbusch, Charles D., Brors, Benedikt, Oehme, Ina, Witt, Olaf, Lübbert, Michael, Mallm, Jan-Philipp, Rippe, Karsten, Will, Rainer, Weichenhan, Dieter, Stoecklin, Georg, Gerhäuser, Clarissa, Oakes, Christopher C., Wang, Ting, Plass, Christoph
Publicado en Nat Genet (2017)