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Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4
During homeostasis, hematopoietic stem cells (HSCs) are mostly kept in quiescence with only minor contribution to steady-state hematopoiesis. However, in stress situations such as infection, chemotherapy, or transplantation, HSCs are forced to proliferate and rapidly regenerate compromised hematopoi...
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| Izdano u: | J Exp Med |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5030798/ https://ncbi.nlm.nih.gov/pubmed/27573814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151713 |
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