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Targeting leukemic stem cells by breaking their dormancy

Transient or long‐term quiescence, the latter referred to as dormancy are fundamental features of at least some adult stem cells. The status of dormancy is likely a critical mechanism for the observed resistance of normal HSCs and leukemic stem cells (LSCs) to anti‐proliferative chemotherapy. Recent...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Essers, Marieke Alida Gertruda, Trumpp, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527930/
https://ncbi.nlm.nih.gov/pubmed/20599449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2010.06.001
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