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Targeting leukemic stem cells by breaking their dormancy

Transient or long‐term quiescence, the latter referred to as dormancy are fundamental features of at least some adult stem cells. The status of dormancy is likely a critical mechanism for the observed resistance of normal HSCs and leukemic stem cells (LSCs) to anti‐proliferative chemotherapy. Recent...

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Bibliografiska uppgifter
I publikationen:Mol Oncol
Huvudupphovsmän: Essers, Marieke Alida Gertruda, Trumpp, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527930/
https://ncbi.nlm.nih.gov/pubmed/20599449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2010.06.001
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